Nucleoside diphosphate kinase beta (Nm23-R1/NDPKbeta) is associated with intermediate filaments and becomes upregulated upon cAMP-induced differentiation of rat C6 glioma.
Mutations in GFAP, encoding glial fibrillary acidic protein, are associated with Alexander disease.
Infantile Alexander disease: spectrum of GFAP mutations and genotype-phenotype correlation.
A novel mutation in glial fibrillary acidic protein gene in a patient with Alexander disease.
Molecular findings in symptomatic and pre-symptomatic Alexander disease patients.
Juvenile Alexander disease with a novel mutation in glial fibrillary acidic protein gene.
A new splice variant of glial fibrillary acidic protein, GFAP epsilon, interacts with the presenilin proteins.
Cellular localization of cyclooxygenase-1 and cyclooxygenase-2 in the normal mouse, rat, and human retina.
Molecular genetic study in Japanese patients with Alexander disease: a novel mutation, R79L.
Functional significance of the specific sites phosphorylated in desmin at cleavage furrow: Aurora-B may phosphorylate and regulate type III intermediate filaments during cytokinesis coordinatedly with Rho-kinase.
Genetic polymorphism and sequence evolution of an alternatively spliced exon of the glial fibrillary acidic protein gene, GFAP.
A novel GFAP mutation and disseminated white matter lesions: adult Alexander disease?
Adult Alexander disease with autosomal dominant transmission: a distinct entity caused by mutation in the glial fibrillary acid protein gene.
Complete sequencing and characterization of 21,243 full-length human cDNAs.
A case of infantile Alexander disease with a milder phenotype and a novel GFAP mutation, L90P.
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Glial fibrillary acidic protein mutations in infantile, juvenile, and adult forms of Alexander disease.
Towards a proteome-scale map of the human protein-protein interaction network.
Human glial fibrillary acidic protein (GFAP): molecular cloning of the complete cDNA sequence and chromosomal localization (chromosome 17) of the GFAP gene.
DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.
Loss of glial fibrillary acidic protein (GFAP) impairs Schwann cell proliferation and delays nerve regeneration after damage.
A case of infantile Alexander disease accompanied by infantile spasms diagnosed by DNA analysis.
Identification and characterization of GFAPkappa, a novel glial fibrillary acidic protein isoform.
Huntingtin interacting proteins are genetic modifiers of neurodegeneration.
Alexander disease with occipital predominance and a novel c.799G>C mutation in the GFAP gene.
GFAP mutations and polymorphisms in 13 unrelated Italian patients affected by Alexander disease.
An adult form of Alexander disease: a novel mutation in glial fibrillary acidic protein.
Adult-onset Alexander disease with progressive ataxia and palatal tremor.
The full-ORF clone resource of the German cDNA Consortium.
Adult-onset Alexander disease : report on a family.
Clinical and genetic study in Chinese patients with Alexander disease.
Human glial fibrillary acidic protein: complementary DNA cloning, chromosome localization, and messenger RNA expression in human glioma cell lines of various phenotypes.
Novel GFAP mutation in patient with adult-onset Alexander disease presenting with spastic ataxia.
Chaperone-mediated autophagy: molecular mechanisms and physiological relevance.
Adult-onset Alexander disease with typical "tadpole" brainstem atrophy and unusual bilateral basal ganglia involvement: a case report and review of the literature.
Identification of regulators of chaperone-mediated autophagy.
-
GFAP stabilizes the CMA translocation complex against chaperone-driven disassembly in the studied mammalian systems.
"GFAP stabilizes
the multimeric translocation complex against chaperone-mediated disassembly"
Down-regulation of glial fibrillary acidic protein and vimentin by RNA interference improves acute urinary dysfunction associated with spinal cord injury in rats.
Characterization of human cDNA and genomic clones for glial fibrillary acidic protein.
GFAP mutations, age at onset, and clinical subtypes in Alexander disease.
Follow-up study of 22 Chinese children with Alexander disease and analysis of parental origin of de novo GFAP mutations.
An RNA polymerase II promoter containing sequences upstream and downstream from the RNA startpoint that direct initiation of transcription from the same site.
Familial adult-onset Alexander disease with a novel mutation (D78N) in the glial fibrillary acidic protein gene with unusual bilateral basal ganglia involvement.
Identification and characterization of citrulline-modified brain proteins by combining HCD and CID fragmentation.
Diagnosis by whole exome sequencing of atypical infantile onset Alexander disease masquerading as a mitochondrial disorder.
A proteome-scale map of the human interactome network.
Widespread macromolecular interaction perturbations in human genetic disorders.
A collagen VI-dependent pathogenic mechanism for Hirschsprung's disease.
Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.
Systematic interactome mapping of acute lymphoblastic leukemia cancer gene products reveals EXT-1 tumor suppressor as a Notch1 and FBWX7 common interactor.
Molecular cloning and primary structure of human glial fibrillary acidic protein.
Changes in brain gene expression shared by scrapie and Alzheimer disease.
An interactome perturbation framework prioritizes damaging missense mutations for developmental disorders.
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.
Impact of intermittent voluntary ethanol consumption during adolescence on the expression of endocannabinoid system and neuroinflammatory mediators.
A reference map of the human binary protein interactome.
Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
A multi-scale map of cell structure fusing protein images and interactions.
Phosphorylation of glial fibrillary acidic protein at the same sites by cleavage furrow kinase and Rho-associated kinase.
Domain-specific phosphorylation of vimentin and glial fibrillary acidic protein by PKN.
Determination of the gene structure of human GFAP and absence of coding region mutations associated with frontotemporal dementia with parkinsonism linked to chromosome 17.
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on curation of immunofluorescence data
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
Nuclear signaling by ERBB4
GFAP gene expression is inhibited by ERBB4:TAB2:NCOR1
Chaperone Mediated Autophagy
GFAP_HUMAN — Glial fibrillary acidic protein
GFAP annotation context, source and product evidence archive
Identification of glial filament protein and vimentin in the same intermediate filament system in human glioma cells.
Effects of Alexander disease-associated mutations on the assembly and organization of GFAP intermediate filaments.