Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Combined Automated Annotation using Multiple IEA Methods
Identification and characterization of a third human, rat, and mouse collagen prolyl 4-hydroxylase isoenzyme.
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Cloning and characterization of the third vertebrate C-P4H alpha-subunit isoform (alpha-III); recombinant human alpha(III) coexpressed with PDI forms an active [alpha(III)]2-beta2 tetramer that hydroxylates collagen chains and a collagen-like peptide.
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Catalytic properties of the alpha(III) C-P4H are very similar to the type I and II C-P4Hs, with peptide-binding properties intermediate between the type I and type II enzymes; alpha(III) mRNA is expressed broadly but at much lower levels than alpha(I)/alpha(II).
A proteome-scale map of the human interactome network.
Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.
A reference map of the human binary protein interactome.
Collagen prolyl 4-hydroxylases modify tumor progression.
P4HA3 promotes clear cell renal cell carcinoma progression via the PI3K/AKT/GSK3beta pathway.
Comprehensive analysis reveals that P4HA3 is a prognostic and diagnostic gastric cancer biomarker that can predict immunotherapy efficacy.
Collagen prolyl 4-hydroxylase subunit alpha member-induced head and neck squamous cell carcinoma aggressiveness is antagonized by LLGL2 via reduced expression of occludin.
A computational analysis of the oncogenic and anti-tumor immunity role of P4HA3 in human cancers.
Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines
Proline hydroxylases hydroxylate Polyprotein
UniProt entry Q7Z4N8 (P4HA3_HUMAN), Prolyl 4-hydroxylase subunit alpha-3