Gene Ontology annotation through association of InterPro records with GO terms
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Gene Ontology annotation based on curation of immunofluorescence data
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
Differential effects of CD40 ligand/trimer stimulation on the ability of dendritic cells to replicate and transmit HIV infection: evidence for CC-chemokine-dependent and -independent mechanisms.
The structural basis for the recognition of diverse receptor sequences by TRAF2.
Recruitment of CD40 and tumor necrosis factor receptor-associated factors 2 and 3 to membrane microdomains during CD40 signaling.
A diverse family of proteins containing tumor necrosis factor receptor-associated factor domains.
Distinct molecular mechanism for initiating TRAF6 signalling.
Disruption of CD40/CD40 ligand interaction with cleavage of CD40 on human gingival fibroblasts by human leukocyte elastase resulting in down-regulation of chemokine production.
Human activation-induced cytidine deaminase is induced by IL-4 and negatively regulated by CD45: implication of CD45 as a Janus kinase phosphatase in antibody diversification.
Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways.
A20 protects from CD40-CD40 ligand-mediated endothelial cell activation and apoptosis.
TNF receptor (TNFR)-associated factor (TRAF) 3 serves as an inhibitor of TRAF2/5-mediated activation of the noncanonical NF-kappaB pathway by TRAF-binding TNFRs.
Expression of the Bcl-2 protein BAD promotes prostate cancer growth.
MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.
The transmembrane activator TACI triggers immunoglobulin class switching by activating B cells through the adaptor MyD88.
Signal pathways in astrocytes activated by cross-talk between of astrocytes and mast cells through CD40-CD40L.
OTUD7B controls non-canonical NF-κB activation through deubiquitination of TRAF3.
Mycobacterium tuberculosis infection of human dendritic cells decreases integrin expression, adhesion and migration to chemokines.
A B-lymphocyte activation molecule related to the nerve growth factor receptor and induced by cytokines in carcinomas.
A proteome-scale map of the human interactome network.
A massively parallel pipeline to clone DNA variants and examine molecular phenotypes of human disease mutations.
Widespread macromolecular interaction perturbations in human genetic disorders.
Phosphorylation of serine 523 on 5-lipoxygenase in human B lymphocytes.
A PPARγ-dependent miR-424/503-CD40 axis regulates inflammation mediated angiogenesis.
Integrin Binding to the Trimeric Interface of CD40L Plays a Critical Role in CD40/CD40L Signaling.
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.
A reference map of the human binary protein interactome.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
CD40 stimulation via CD40 ligand enhances adenovirus-mediated tumour immunogenicity including 'find-me', 'eat-me', and 'kill-me' signalling.
Multimodal cell maps as a foundation for structural and functional genomics.
A novel RING finger protein interacts with the cytoplasmic domain of CD40.
Cleavage of membrane-bound CD40 ligand is not required for inducing B cell proliferation and differentiation.
Identification of TRAF6, a novel tumor necrosis factor receptor-associated factor protein that mediates signaling from an amino-terminal domain of the CD40 cytoplasmic region.
CD40 ligand on activated platelets triggers an inflammatory reaction of endothelial cells.
TRAF2 ubiquitinates cIAP1,2 in cIAP1,2:TRAF1:TRAF2:TRAF3:NIK
K63polyUb-cIAP1,2 ubiquitinates TRAF3
Protesomal degradation of K48polyUb-TRAF3
TRAF2:TRAF1:cIAP1,2:TRAF3:NIK regulatory complex binds CD40
Reviewed human CD40 UniProt record P25942
Regulation of CD40 function by its isoforms generated through alternative splicing.
Mutations of CD40 gene cause an autosomal recessive form of immunodeficiency with hyper IgM.
CD40 is constitutively expressed on platelets and provides a novel mechanism for platelet activation.