GPD2 (YOL059W, UniProt P41911) notes

Activity / role

• NAD-GPDH isoenzyme PMID:9171333; Km NADH 18 uM, DHAP 0.86 mM [UniProt:P41911]
• Anaerobic redox role, not osmotic PMID:9171333; PMID:9171333
• Double mutant PMID:9171333
• Overexpression as effective as GPD1 PMID:11676566

Localization

• Mito presequence PMID:15210723; import confirmed PMID:17054397
• Shuttle component PMID:10781551

Curation observations

• IBA nucleus is inherited only from Gpd1p's stress relocation (PTS2-dependent) -> marked over-annotated.
• glycerol metabolic process IMP -> MODIFY to glycerol biosynthetic process (GPD2 has no direct GO:0006114 row).