Gene Ontology annotation through association of InterPro records with GO terms

Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity

Annotation inferences using phylogenetic trees

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

Gene Ontology annotation based on curation of immunofluorescence data

Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara

Electronic Gene Ontology annotations created by ARBA machine learning models

Combined Automated Annotation using Multiple IEA Methods

Isolation, characterization and expression of a human brain mitochondrial glutaminase cDNA.

Cloning and analysis of unique human glutaminase isoforms generated by tissue-specific alternative splicing.

Brain-specific BNIP-2-homology protein Caytaxin relocalises glutaminase to neurite terminals and reduces glutamate levels.

The nuclear receptor FXR regulates hepatic transport and metabolism of glutamine and glutamate.

Full-length human glutaminase in complex with an allosteric inhibitor.

Mitochondrial localization and structure-based phosphate activation mechanism of Glutaminase C with implications for cancer metabolism.

Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism.

Structural basis for the active site inhibition mechanism of human kidney-type glutaminase (KGA).

Design and evaluation of novel glutaminase inhibitors.

The origin and evolution of human glutaminases and their atypical C-terminal ankyrin repeats.

Characterization of the interactions of potent allosteric inhibitors with glutaminase C, a key enzyme in cancer cell glutamine metabolism.

GLS hyperactivity causes glutamate excess, infantile cataract and profound developmental delay.

Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context.

glutamine + H2O => glutamate + NH4+ (GLS)