GO_REF:0000002
Gene Ontology annotation through association of InterPro records with GO terms
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000107
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
GO_REF:0000116
Automatic Gene Ontology annotation based on Rhea mapping
GO_REF:0000117
Electronic Gene Ontology annotations created by ARBA machine learning models
GO_REF:0000120
Combined Automated Annotation using Multiple IEA Methods
PMID:11279118
Regulation of stress-responsive mitogen-activated protein (MAP) kinase pathways by TAO2.
PMID:11980910
Mirk protein kinase is activated by MKK3 and functions as a transcriptional activator of HNF1alpha.
PMID:17255949
Mxi2 promotes stimulus-independent ERK nuclear translocation.
PMID:19805025
CIB1 functions as a Ca(2+)-sensitive modulator of stress-induced signaling by targeting ASK1.
PMID:19946888
Defining the membrane proteome of NK cells.
PMID:20067578
MKK6 binds and regulates expression of Parkinson's disease-related protein LRRK2.
PMID:20173330
LRRK2 and the stress response: interaction with MKKs and JNK-interacting proteins.
PMID:21044950
Genome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cells.
PMID:21771788
Positive regulation of apoptosis signal-regulating kinase 1 signaling by ZPR9 protein, a zinc finger protein.
PMID:22696064
miR-20a represses endothelial cell migration by targeting MKK3 and inhibiting p38 MAP kinase activation in response to VEGF.
PMID:23602568
The protein interaction landscape of the human CMGC kinase group.
PMID:27402810
Regulation of Hippo signalling by p38 signalling.
PMID:31980649
Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRAS(G13D).
PMID:32707033
Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases.
PMID:33961781
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
PMID:7839144
Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms.
PMID:8622669
MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway.
Reactome:R-HSA-2559583
Cellular Senescence
Reactome:R-HSA-3228469
MAP3K5 phosphorylates MKK3 and MKK6
Reactome:R-HSA-3238999
Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK5
Reactome:R-HSA-450296
Phosphorylated MKK3/MKK6 migrates to nucleus
Reactome:R-HSA-450302
activated TAK1 mediates p38 MAPK activation
Reactome:R-HSA-450333
Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3
Reactome:R-HSA-450346
activated human TAK1 phosphorylates MKK3/MKK6
Reactome:R-HSA-5211400
Anthrax lef cleaves target cell MAP2K3 (MEK3)
file:human/MAP2K3/MAP2K3-uniprot.txt
UniProt record for human MAP2K3
file:human/MAP2K3/MAP2K3-deep-research-falcon.md
Falcon deep research report for human MAP2K3