file:human/ATP6V0D1/ATP6V0D1-uniprot.txt
UniProt record for human ATP6V0D1 (P61421)
file:human/ATP6V0D1/ATP6V0D1-deep-research-manual.md
Manual deep research fallback for ATP6V0D1
file:human/ATP6V0D1/ATP6V0D1-notes.md
Local curation notes for ATP6V0D1
GO_REF:0000002
Gene Ontology annotation through association of InterPro records with GO terms
GO_REF:0000024
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000044
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
GO_REF:0000107
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
GO_REF:0000108
Automatic assignment of GO terms using logical inference, based on on inter-ontology links
GO_REF:0000117
Electronic Gene Ontology annotations created by ARBA machine learning models
GO_REF:0000120
Combined Automated Annotation using Multiple IEA Methods
PMID:11118322
Structure of the VPATPD gene encoding subunit D of the human vacuolar proton ATPase.
PMID:16713569
A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.
PMID:17897319
Integral and associated lysosomal membrane proteins.
PMID:18752060
The d subunit plays a central role in human vacuolar H(+)-ATPases.
PMID:19056867
Large-scale proteomics and phosphoproteomics of urinary exosomes.
PMID:19199708
Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
PMID:20093472
Requirement of prorenin receptor and vacuolar H+-ATPase-mediated acidification for Wnt signaling.
PMID:21844891
A SNX10/V-ATPase pathway regulates ciliogenesis in vitro and in vivo.
PMID:22053050
mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H(+)-ATPase.
PMID:22982048
Lipofuscin is formed independently of macroautophagy and lysosomal activity in stress-induced prematurely senescent human fibroblasts.
PMID:23533145
In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.
PMID:28296633
The vacuolar-ATPase complex and assembly factors, TMEM199 and CCDC115, control HIF1α prolyl hydroxylation by regulating cellular iron levels.
PMID:29644770
TMEM55B contributes to lysosomal homeostasis and amino acid-induced mTORC1 activation.
PMID:30374053
TMEM9 promotes intestinal tumorigenesis through vacuolar-ATPase-activated Wnt/β-catenin signalling.
PMID:32296183
A reference map of the human binary protein interactome.
PMID:32814053
Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains.
Reactome:R-HSA-1222516
Intraphagosomal pH is lowered to 5 by V-ATPase
Reactome:R-HSA-1791184
Expression of ATP6VOD1
Reactome:R-HSA-5252133
ATP6AP1 binds V-ATPase
Reactome:R-HSA-74723
Endosome acidification
Reactome:R-HSA-917841
Acidification of Tf:TfR1 containing endosome
Reactome:R-HSA-9639286
RRAGC,D exchanges GTP for GDP
Reactome:R-HSA-9640167
RRAGA,B exchanges GDP for GTP
Reactome:R-HSA-9640168
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine
Reactome:R-HSA-9640175
v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine
Reactome:R-HSA-9640195
RRAGA,B hydrolyzes GTP
Reactome:R-HSA-9645598
RRAGC,D hydrolyzes GTP
Reactome:R-HSA-9645608
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1
Reactome:R-HSA-9646468
mTORC1 binds RHEB:GTP
Reactome:R-HSA-9858932
MITF-M-dependent ATP6V0D1 gene expression
PMID:33065002
Structures of a Complete Human V-ATPase Reveal Mechanisms of Its Assembly.