YDA / YODA (At1g63700, Q9CAD5) curation notes

Session 2026-10-06 (stomatal_lineage_development module). Falcon deep research failed (HTTP 402).

Key findings

• yda null -> excess stomata; constitutive YDA -> no stomata PMID:15178800.
• MKK4/MKK5-MPK3/MPK6 module downstream of YODA PMID:17259259.
• MPK targets SPCH PMID:19008449; SCRM scaffolds MPK3/6 to SPCH PMID:31235876.
• BIN2 phosphorylates YDA and inhibits its phosphorylation of MKK4 PMID:22307275.
• BASL recruits YDA and MPK3/6 to the cortex PMID:25843888; YDA-YFP at plasma membrane / polarized at cortex.
• Zygote elongation and suspensor fate PMID:14718171; interacts with SSP PMID:28821747; inflorescence architecture downstream of ER PMID:23263767.

Curation decisions

• Core MF: MAP kinase kinase kinase activity GO:0004709 (IBA accepted). Core BPs: MAPK cascade; negative regulation of stomatal complex development (NEW; stomatal complex morphogenesis IMP MODIFIED); suspensor development (accepted).
• Protein binding: BIN2 and MPK6 rows MODIFIED to protein kinase binding; BASL, SSP (pseudokinase) and MASS rows REMOVED.
• No GO-CAM models contain YDA.