ALD6 (YPL061W, UniProt P54115) notes

Identity

• Cytosolic Mg2+-activated ACDH PMID:9392076; "ALDH1" (chromosome XVI) in Wang et al. PMID:9473035

Activity

• NADP-specific PMID:9473035; Km acetaldehyde 24 uM [UniProt:P54115]

Processes

• Acetate formation (PDH bypass) PMID:11870853
• Ethanol utilization PMID:9392076
• Cytosolic NADPH, redundant with Zwf1 PMID:12584194
• Salt/FK506 phenotype PMID:15146068

Curation observations

• IBA NAD+-ALDH (PTN000192666) marked over-annotated: NADP specificity diverged.
• IBA is_active_in mitochondrion (PTN000916385) marked over-annotated: no leader; activity cytosolic. HDA/IDA mitochondrion kept non-core.
• Bifid shunt RCA removed.