Gene Ontology annotation through association of InterPro records with GO terms
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
Mechanism of action and in vivo role of platelet-derived growth factor.
PDGF-C is a new protease-activated ligand for the PDGF alpha-receptor.
Platelet-derived growth factor C (PDGF-C), a novel growth factor that binds to PDGF alpha and beta receptor.
Effect of platelet-derived growth factor isoforms in rat metanephric mesenchymal cells.
Adipocyte-derived plasma protein adiponectin acts as a platelet-derived growth factor-BB-binding protein and regulates growth factor-induced common postreceptor signal in vascular smooth muscle cell.
VEGF-C is a trophic factor for neural progenitors in the vertebrate embryonic brain.
Vascular endothelial growth factor can signal through platelet-derived growth factor receptors.
PDGF receptor-{beta} modulates metanephric mesenchyme chemotaxis induced by PDGF AA.
PDGF induces c-myc mRNA expression in MG-63 human osteosarcoma cells but does not stimulate cell replication.
Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network.
Isolation of a novel receptor cDNA establishes the existence of two PDGF receptor genes.
Collagen-induced binding to human platelets of platelet-derived growth factor leading to inhibition of P43 and P20 phosphorylation.
A common PDGF receptor is activated by homodimeric A and B forms of PDGF.
Comparison of biological properties and transforming potential of human PDGF-A and PDGF-B chains.
Platelet-derived growth factor: purification and partial characterization.
cDNA sequence and chromosomal localization of human platelet-derived growth factor A-chain and its expression in tumour cell lines.
Platelet-derived growth factor: identification of constituent polypeptide chains.
Mechanism of platelet-derived growth factor (PDGF) AA, AB, and BB binding to alpha and beta PDGF receptor.
Type I, II, III, IV, V, and VI collagens serve as extracellular ligands for the isoforms of platelet-derived growth factor (AA, BB, and AB).
Platelet-derived growth factor beta-receptors can both promote and inhibit chemotaxis in human vascular smooth muscle cells.
Activated PLC gamma dissociates from the PDGF receptor
Phosphorylation of PLCgamma by PDGFR
PLC-gamma binds to the active receptor
PDGF dimer binds two receptors simultaneously
SHP2 binds to the active receptor
PI3-kinase binds to the active receptor
PI3K catalyses the phosphorylation of PIP2 to PIP3
SH2 domain of Src binds to the active receptor
GRB2:SOS1 complex binds to the active receptor
SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS)
PI3K phosphorylates PIP2 to PIP3
HSPG2 binds FGF2(10-155), Fibronectn matrix, Transthyretin tetramer, PDGFA homodimer, PDGFB homodimer
PI3K inhibitors block PI3K catalytic activity
STAT binds to the active receptor
p130Cas and C3G bind PDGFR bound Crk
Translocation of PDGF from ER to Golgi
PDGF binds to extracellular matrix proteins
Grb7 binds to the active PDGF receptor
Crk binds to the active PDGF receptor
Nck binds to the active PDGF receptor
Autophosphorylation of PDGF alpha receptors
Autophosphorylation of PDGF alpha/beta receptors
Exocytosis of platelet alpha granule contents
RAS GEFs promote RAS nucleotide exchange
PTPN12 dephosphorylates PDGFRB at Y1021
NFE2L2 dependent PDGFA expression
Falcon deep research synthesis for PDGFA