CAL (CAULIFLOWER, AGL10, At1g26310; UniProt Q39081) curation notes

2026-10-05 — initial review (floral_meristem_identity module)

• Identity check: CAL-uniprot.txt is CAL_ARATH, Q39081, At1g26310, synonym AGL10. Correct protein.
• Falcon deep research was attempted (just deep-research-falcon ARATH CAL) but the provider exited with code 1; no deep-research file was produced. Notes below are from cached publications only.

Core biology

• CAL encodes a MADS-domain protein closely related to AP1; partial redundancy with AP1 in floral meristem formation
  PMID:7824951
  PMID:7824951
• Brassica oleracea var. botrytis curd phenotype linked to non-functional CAL homolog
  PMID:7824951.
• ap1 cal ful triple mutant makes leafy shoots instead of flowers; mechanism is failure to up-regulate LFY plus ectopic TFL1
  PMID:10648231
• CAL listed among the floral meristem identity genes with LFY and AP1
  PMID:10368173
• AP1/CAL used as baits in yeast two-hybrid; MADS heterodimers PMID:11439126; matrix Y2H gives CAL-SOC1 heterodimer PMID:15805477.

Annotation decisions (summary)

• MF: core = GO:0000981 (IBA, accepted). Generic DNA binding / GO:0003700 IEA -> MODIFY to more specific terms.
• protein binding (SOC1 partner) -> MODIFY to GO:0046982 protein heterodimerization activity.
• BP: GO:0010582 floral meristem determinacy (IBA; CAL is in its own WITH/FROM which is expected) ACCEPT; GO:0009911 positive regulation of flower development ACCEPT.
• No GO term exists for "floral meristem identity specification"; AP1 review already proposes one. Not duplicated here.