Electronic Gene Ontology annotations created by ARBA machine learning models
Leaps and lulls in the developmental transcriptome of Dictyostelium discoideum.
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cotB is used as a canonical marker of prespore cell-type differentiation in Dictyostelium development.
"The genes cotB and ecmB are often used to mark the differentiation of prespore and prestalk cell-types, respectively"
Plasma membrane proteins of Dictyostelium: the spore coat proteins.
Protein kinase A is a positive regulator of spore coat gene transcription in Dictyostelium.
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cotB encodes a major spore coat protein whose transcription is controlled by PKA acting via a CA-rich-element DNA-binding factor.
"The cotA, cotB, and cotC genes encode the major spore coat proteins of Dictyostelium"
Structural roles of the spore coat proteins in Dictyostelium discoideum.
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Knockouts of the major spore coat proteins (including SP70) yield viable but more porous spores, indicating a structural role in the coat.
"the spores are more porous which might make them at risk to predators before germination"
PsB multiprotein complex of Dictyostelium discoideum. Demonstration of cellulose binding activity and order of protein subunit assembly.
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The spore coat glycoproteins form a preassembled multiprotein complex (PsB) stored in prespore vesicles and later secreted into the coat.
"the complex is synchronously secreted from the prespore vesicles and incorporated into the spore coat"
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The assembled PsB complex has specific cellulose binding activity that requires all subunits to be assembled.
"the protein subunits must be assembled for cellulose binding activity"