Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

file:BPT4/ac/ac-uniprot.txt

UniProtKB record for P18924 (Y522_BPT4)

Protein ac (gp52.2) is a 51-amino-acid predicted multi-pass host membrane protein whose mutation confers resistance to acridine inhibition of phage development.

"DISRUPTION PHENOTYPE: Mutations in the gene confer resistance to acridine-inhibition of phage development. {ECO:0000269|PubMed:9560385}."
Protein ac is predicted to be a multi-pass integral protein of the host membrane.

"SUBCELLULAR LOCATION: Host membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}."

file:BPT4/ac/ac-deep-research-falcon.md

Deep research summary for Enterobacteria phage T4 gene ac (52.2)

Mutations in T4 gene ac (52.2) overcome acriflavin inhibition and alter the permeability and uptake of acridines in infected Escherichia coli cells.

"**Acriflavin inhibits T4 development**, and **mutations in the T4 ac gene (gene 52.2) overcome acriflavin inhibition and allow phage development**"
Loss-of-function mutations in gene ac (52.2) confer resistance to acriflavin inhibition of T4 development.

"**Acriflavin inhibits T4 development**, and **mutations in the T4 ac gene (gene 52.2) overcome acriflavin inhibition and allow phage development**"