GO_REF:0000002

Gene Ontology annotation through association of InterPro records with GO terms

file:NICAT/NaA622/NaA622-uniprot.txt

UniProt entry A0A314KUK7 for Nicotiana attenuata A622 candidate

UniProt identifies A0A314KUK7 as an A622-like isoflavone reductase family protein

"DE SubName: Full=Isoflavone reductase -like a622 ;"

file:NICAT/NaA622/NaA622-notes.md

NaA622 literature review notes

A622 is the late-pathway NaGR reductase in the completed nicotine synthase cascade

"The full nicotine glucosylation preprint redefines A622 as NaGR, a nicotinic acid N-glucoside reductase in the four-enzyme nicotine synthase cascade, making A622 a directly supported late-pathway catalyst rather than a generic oxidoreductase placeholder."
A622 has direct structural and mechanistic support in the glucosylation model

"The same paper provides strong mechanistic support for A622 by solving A622/NaGR with nicotinic acid N-glucoside and by showing that A622 loss blocks the pathway at nicotinic acid N-glucoside."