Gene Ontology annotation through association of InterPro records with GO terms
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Gene Ontology annotation based on curation of immunofluorescence data
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Automatic Gene Ontology annotation based on Rhea mapping
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
The protein kinase A anchoring protein mAKAP coordinates two integrated cAMP effector pathways.
TGF-beta activates ERK5 in human renal epithelial cells.
Erk5 activation elicits a vasoprotective endothelial phenotype via induction of Kruppel-like factor 4 (KLF4).
Pharmacological inhibition of BMK1 suppresses tumor growth through promyelocytic leukemia protein.
BMK1 is involved in the regulation of p53 through disrupting the PML-MDM2 interaction.
Laminar flow activation of ERK5 protein in vascular endothelium leads to atheroprotective effect via NF-E2-related factor 2 (Nrf2) activation.
Canonical and kinase activity-independent mechanisms for extracellular signal-regulated kinase 5 (ERK5) nuclear translocation require dissociation of Hsp90 from the ERK5-Cdc37 complex.
A proteome-scale map of the human interactome network.
Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.
Architecture of the human interactome defines protein communities and disease networks.
Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRAS(G13D).
A reference map of the human binary protein interactome.
Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
Systematic discovery of mutation-directed neo-protein-protein interactions in cancer.
Primary structure of BMK1: a new mammalian map kinase.
Components of a new human protein kinase signal transduction pathway.
ERK5 translocates to the nucleus
ERK1/2/5 activate RSK1/2/3
ERKs are inactivated by protein phosphatase 2A
ERKs are inactivated by dual-specific phosphatases (DUSPs)
2x p-5Y-RET:GDNF:GFRA complexes bind RET interactors
BMK1/ERK5 regulates serum-induced early gene expression through transcription factor MEF2C.
Bmk1/Erk5 is required for cell proliferation induced by epidermal growth factor.
BMK1 mediates growth factor-induced cell proliferation through direct cellular activation of serum and glucocorticoid-inducible kinase.
ERK5 is a novel type of mitogen-activated protein kinase containing a transcriptional activation domain.
Paradoxical activation of the protein kinase-transcription factor ERK5 by ERK5 kinase inhibitors.
Interaction of myocyte enhancer factor 2 (MEF2) with a mitogen-activated protein kinase, ERK5/BMK1.
Erk5 null mice display multiple extraembryonic vascular and embryonic cardiovascular defects.
Targeted deletion of BMK1/ERK5 in adult mice perturbs vascular integrity and leads to endothelial failure.
Novel role of C terminus of Hsc70-interacting protein (CHIP) ubiquitin ligase on inhibiting cardiac apoptosis and dysfunction via regulating ERK5-mediated degradation of inducible cAMP early repressor.
Falcon deep research report on MAPK7