Gene Ontology annotation through association of InterPro records with GO terms

Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity

Annotation inferences using phylogenetic trees

Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara

Electronic Gene Ontology annotations created by ARBA machine learning models

Combined Automated Annotation using Multiple IEA Methods

Cooperative activation of atrial naturetic peptide promoter by dHAND and MEF2C.

Phox2 and dHAND transcription factors select shared and unique target genes in the noradrenergic cell type.

Nfat and miR-25 cooperate to reactivate the transcription factor Hand2 in heart failure.

A proteome-scale map of the human interactome network.

Impact of cytosine methylation on DNA binding specificities of human transcription factors.

Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.

Molecular cloning of the human HAND2 gene.

The bHLH transcription factor dHAND controls Sonic hedgehog expression and establishment of the zone of polarizing activity during limb development.

The combinatorial activities of Nkx2.5 and dHAND are essential for cardiac ventricle formation.

The basic helix-loop-helix factor, HAND2, functions as a transcriptional activator by binding to E-boxes as a heterodimer.

The transcription factors GATA4 and dHAND physically interact to synergistically activate cardiac gene expression through a p300-dependent mechanism.

Misexpression of dHAND induces ectopic digits in the developing limb bud in the absence of direct DNA binding.

The basic-helix-loop-helix transcription factor HAND2 directly regulates transcription of the atrial naturetic peptide gene.

Altered Twist1 and Hand2 dimerization is associated with Saethre-Chotzen syndrome and limb abnormalities.

The basic helix-loop-helix factor Hand 2 regulates autonomic nervous system development.

Conditional deletion of Hand2 reveals critical functions in neurogenesis and cell type-specific gene expression for development of neural crest-derived noradrenergic sympathetic ganglion neurons.

Cardiac neural crest expression of Hand2 regulates outflow and second heart field development.

Regulation of cardiac mesodermal and neural crest development by the bHLH transcription factor, dHAND.