The Gfi-1B proto-oncoprotein represses p21WAF1 and inhibits myeloid cell differentiation.
The human homologue (GFI1B) of the chicken GFI gene maps to chromosome 9q34.13-A locus frequently altered in hematopoietic diseases.
Erythroid expansion mediated by the Gfi-1B zinc finger protein: role in normal hematopoiesis.
Gfi-1 attaches to the nuclear matrix, associates with ETO (MTG8) and histone deacetylase proteins, and represses transcription using a TSA-sensitive mechanism.
DNA sequence and analysis of human chromosome 9.
GATA-1 and NF-Y cooperate to mediate erythroid-specific transcription of Gfi-1B gene.
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
GATA-1 forms distinct activating and repressive complexes in erythroid cells.
GATA-1 mediates auto-regulation of Gfi-1B transcription in K562 cells.
Gfi1b alters histone methylation at target gene promoters and sites of gamma-satellite containing heterochromatin.
A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.
Gene expression patterns define novel roles for E47 in cell cycle progression, cytokine-mediated signaling, and T lineage development.
The consensus coding sequences of human breast and colorectal cancers.
Growth factor-independent 1B gene (GFI1B) is overexpressed in erythropoietic and megakaryocytic malignancies and increases their proliferation rate.
Growth factor independent 1B (Gfi1b) is an E2A target gene that modulates Gata3 in T-cell lymphomas.
GATA-1 and Gfi-1B interplay to regulate Bcl-xL transcription.
Gfi1 ubiquitination and proteasomal degradation is inhibited by the ubiquitin ligase Triad1.
A short Gfi-1B isoform controls erythroid differentiation by recruiting the LSD1-CoREST complex through the dimethylation of its SNAG domain.
GFI1B mutation causes a bleeding disorder with abnormal platelet function.
A dominant-negative GFI1B mutation in the gray platelet syndrome.
Impact of cytosine methylation on DNA binding specificities of human transcription factors.
Zinc finger protein Gfi-1b
Protein kinase C-binding protein NELL2
Centrosomal P4.1-associated protein
Zinc finger protein ZFPM1
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Gene Ontology annotation based on curation of immunofluorescence data
Automatic assignment of GO terms using logical inference, based on on inter-ontology links
Electronic Gene Ontology annotations created by ARBA machine learning models
GFI1B selected primary evidence and source-context distinctions