file:genes/STAHA/lnuA/lnuA-uniprot.txt

UniProt flat file for lnuA/linA (P06107)

UniProt/CARD identifies this entry as lnuA/linA, a lincosamide antibiotic-inactivation determinant.

"DR CARD; ARO:3002835; lnuA; ARO:0001004; antibiotic inactivation."

Nucleotide sequence of gene linA encoding resistance to lincosamides in Staphylococcus haemolyticus.

The original linA sequence paper supports the lincosamide resistance and inactivation phenotype.

"which confers resistance to lincomycin by inactivating it in Staphylococcus haemolyticus."

Inactivation of lincosaminide antibiotics in Staphylococcus. Identification of lincosaminide O-nucleotidyltransferases and comparison of the corresponding resistance genes.

The biochemical follow-up identifies LinA-family lincosamide O-nucleotidyltransferase products.

"inactivation of lincomycin gave rise to lincomycin 3-(5'-adenylate)"

file:projects/ANTIMICROBIAL_RESISTANCE/aro2go.sssom.yaml

Curated ARO to GO mapping set for AMR gene families

The AMR mapping records Lnu/lincosamide nucleotidyltransferase as a GO molecular-function gap.

"GO has no lincosamide (O-)nucleotidyltransferase MF term"