Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Gene Ontology annotation based on curation of immunofluorescence data
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
A predicted amphipathic helix mediates plasma membrane localization of GRK5.
Characterization of G-protein coupled receptor kinase interaction with the neurokinin-1 receptor using bioluminescence resonance energy transfer.
The G-protein-coupled receptor kinase 5 inhibits NFkappaB transcriptional activity by inducing nuclear accumulation of IkappaB alpha.
Beta-arrestin1 phosphorylation by GRK5 regulates G protein-independent 5-HT4 receptor signalling.
Role for the regulator of G-protein signaling homology domain of G protein-coupled receptor kinases 5 and 6 in beta 2-adrenergic receptor and rhodopsin phosphorylation.
G-protein-coupled receptor kinase 5 phosphorylates p53 and inhibits DNA damage-induced apoptosis.
G-protein coupled receptor kinase 5 regulates prostate tumor growth.
GRK5 deficiency decreases diet-induced obesity and adipogenesis.
Cloning and expression of GRK5: a member of the G protein-coupled receptor kinase family.
Expression, purification, and characterization of the G protein-coupled receptor kinase GRK5.
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Purified GRK5 phosphorylates M2 as one directly tested receptor substrate.
"GRK5 phosphorylates the beta 2-adrenergic receptor (beta 2AR), m2 muscarinic
cholinergic receptor, and rhodopsin in an agonist-dependent manner"
Involvement of G protein-coupled receptor kinase 5 in homologous desensitization of the thyrotropin receptor.
Structure-function analysis of G protein-coupled receptor kinase-5. Role of the carboxyl terminus in kinase regulation.
GPCR downstream signalling
ADRB2 in ADRB2:GRK complex is phosphorylated
ADRB2:GRK complex dissociates to Phosphorylated ADRB2
GRKs bind ADRB2:Catecholamine