Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Electronic Gene Ontology annotations created by transferring manual GO annotations between related proteins based on shared sequence features
Combined Automated Annotation using Multiple IEA Methods
The AhpC and AhpD antioxidant defense system of Mycobacterium tuberculosis.
Metabolic enzymes of mycobacteria linked to antioxidant defense by a thioredoxin-like protein.
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Direct identification of an Lpd–DlaT (then SucB)–AhpD–AhpC redox relay.
"The peroxiredoxin alkyl hydroperoxide reductase (AhpC) is linked to Lpd and SucB by an adaptor protein, AhpD."
Comprehensive proteomic profiling of the membrane constituents of a Mycobacterium tuberculosis strain.
Multiple thioredoxin-mediated routes to detoxify hydroperoxides in Mycobacterium tuberculosis.
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Abstract directly establishes TrxR–TrxC–AhpC peroxide turnover and distinguishes Tpx donor breadth.
"NADPH-driven hydroperoxide reduction by AhpC that is mediated by thioredoxin reductase and thioredoxin C"
Intermolecular interactions in the AhpC/AhpD antioxidant defense system of Mycobacterium tuberculosis.
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Target AhpC/AhpD mutants and reversible mixed disulfides resolve their direct exchange.
"A key step in the reduction of oxidized AhpC by reduced AhpD is formation of a disulfide cross-link between Cys61 of AhpC and Cys133 of AhpD."
UniProtKB P9WQB5 ahpD from Mycobacterium tuberculosis H37Rv
The crystal structure of Mycobacterium tuberculosis alkylhydroperoxidase AhpD, a potential target for antitubercular drug design.
The mechanism of Mycobacterium tuberculosis alkylhydroperoxidase AhpD as defined by mutagenesis, crystallography, and kinetics.