Gene Ontology annotation through association of InterPro records with GO terms

Annotation inferences using phylogenetic trees

Gene Ontology annotation based on curation of immunofluorescence data

Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara

Electronic Gene Ontology annotations created by ARBA machine learning models

Combined Automated Annotation using Multiple IEA Methods

The 2.0 A structure of human hypoxanthine-guanine phosphoribosyltransferase in complex with a transition-state analog inhibitor.

The crystal structure of free human hypoxanthine-guanine phosphoribosyltransferase reveals extensive conformational plasticity throughout the catalytic cycle.

Towards a proteome-scale map of the human protein-protein interaction network.

An empirical framework for binary interactome mapping.

Inhibition of hypoxanthine-guanine phosphoribosyltransferase by acyclic nucleoside phosphonates: a new class of antimalarial therapeutics.

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.

A proteome-scale map of the human interactome network.

A massively parallel pipeline to clone DNA variants and examine molecular phenotypes of human disease mutations.

Widespread macromolecular interaction perturbations in human genetic disorders.

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.

A reference map of the human binary protein interactome.

Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains.

Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.

Human hypoxanthine-guanine phosphoribosyltransferase (HGPRT): purification and properties.

Isolation and characterization of a full-length expressible cDNA for human hypoxanthine phosphoribosyl transferase.

The crystal structure of human hypoxanthine-guanine phosphoribosyltransferase with bound GMP.

Dopamine transporters are markedly reduced in Lesch-Nyhan disease in vivo.

Catalysis in human hypoxanthine-guanine phosphoribosyltransferase: Asp 137 acts as a general acid/base.

Purine metabolism in female heterozygotes for hypoxanthine-guanine phosphoribosyltransferase deficiency.

HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP

Defective HPRT1 does not convert guanine or hypoxanthine to GMP or IMP

HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP