Gene Ontology annotation through association of InterPro records with GO terms

Annotation inferences using phylogenetic trees

Electronic Gene Ontology annotations created by ARBA machine learning models

Combined Automated Annotation using Multiple IEA Methods

The Pseudomonas aeruginosa pirA gene encodes a second receptor for ferrienterobactin and synthetic catecholate analogues.

PirA is a second ferric-enterobactin receptor, redundant with PfeA.

"Hence, we confirmed that pirA represents a second P. aeruginosa ferric-enterobactin receptor."

PMID:28137795

Structure and Function of the PiuA and PirA Siderophore-Drug Receptors from Pseudomonas aeruginosa and Acinetobacter baumannii.

A crystal structure of P. aeruginosa PirA was determined.

"The crystal structures of PiuA and PirA from A. baumannii and their orthologues from P. aeruginosa were determined."

PMID:33350053

Opportunistic use of catecholamine neurotransmitters as siderophores to access iron by Pseudomonas aeruginosa.

PirA is one of two TBDTs that import catecholamine-chelated iron.

"Bacterial growth assays under strong iron-restricted conditions and with numerous mutants showed that the TBDTs involved are PiuA and PirA."