Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Combined Automated Annotation using Multiple IEA Methods
Novel target genes of PsrA transcriptional regulator of Pseudomonas aeruginosa.
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PsrA binds a palindromic motif and regulates targets positively and negatively; it autorepresses and regulates rpoS.
"Promoters PA0506 and PA2952-PA2951 were regulated negatively whereas promoters of PA2953 and PA3571 were regulated positively by PsrA"
PsrA is a positive transcriptional regulator of the type III secretion system in Pseudomonas aeruginosa.
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PsrA is required for full exsCEBA and exoS transcription.
"Using transcriptional fusions, we demonstrated that PsrA is required for the full activation of transcription of the TTSS regulatory operon exsCEBA and effector exoS"
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T3SS effector secretion falls in the psrA mutant.
"The psrA mutant showed a marked decrease in the secretion of the type III effectors"
The Pseudomonas aeruginosa PsrA responds to long-chain fatty acid signals to regulate the fadBA5 beta-oxidation operon.
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PsrA binds the fadBA5 promoter; LCFAs disrupt the binding.
"Electrophoretic mobility shift assays indicate specific binding of PsrA to the fadBA5 promoter region. This binding is disrupted by specific LCFAs"
psrA (PA3006) review notes