Gene Ontology annotation through association of InterPro records with GO terms

Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity

Annotation inferences using phylogenetic trees

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

Gene Ontology annotation based on curation of immunofluorescence data

Combined Automated Annotation using Multiple IEA Methods

A novel subfamily of mouse cytosolic carboxypeptidases.

Cytosolic carboxypeptidase 1 is involved in processing α- and β-tubulin.

Functional segregation and emerging role of cilia-related cytosolic carboxypeptidases (CCPs).

Cytosolic carboxypeptidase 5 removes α- and γ-linked glutamates from tubulin.

Klf4 glutamylation is required for cell reprogramming and early embryonic development in mice.

Loss of tubulin deglutamylase CCP1 causes infantile-onset neurodegeneration.

A family of protein-deglutamylating enzymes associated with neurodegeneration.

Mitochondrial dysfunction in NnaD mutant flies and Purkinje cell degeneration mice reveals a role for Nna proteins in neuronal bioenergetics.

Identification of CRM1-dependent Nuclear Export Cargos Using Quantitative Mass Spectrometry.

Purkinje cell degeneration (pcd) phenotypes caused by mutations in the axotomy-induced gene, Nna1.

The Purkinje cell degeneration 5J mutation is a single amino acid insertion that destabilizes Nna1 protein.

CCP1 promotes mitochondrial fusion and motility to prevent Purkinje cell neuron loss in pcd mice.

UniProt Q9UPW5 AGTPBP1 record

AGTPBP1 manual evidence and provenance notes