Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniPathway vocabulary mapping
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
UniProtKB Q9LR30 (GGAT1) entry
Proteomic analysis of leaf peroxisomal proteins in greening cotyledons of Arabidopsis thaliana.
Alanine aminotransferase homologs catalyze the glutamate:glyoxylate aminotransferase reaction in peroxisomes of Arabidopsis.
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Recombinant GGT1/GGT2 catalyse Glu:glyoxylate, Ala:glyoxylate, Glu:pyruvate and Ala:2-oxoglutarate transaminations; GGT activity is exclusively peroxisomal.
"Four aminotransferase activities were specifically associated with GGT1 and GGT2, using the substrate pairs glutamate (Glu):glyoxylate, Ala:glyoxylate, Glu:pyruvate, and Ala:2-oxoglutarate."
Identification of photorespiratory glutamate:glyoxylate aminotransferase (GGAT) gene in Arabidopsis.
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AOAT1-GFP is peroxisomal via PTS1; aoat1-1 knockout loses most leaf GGAT activity and shows a photorespiratory-like, high-CO2-rescued growth phenotype.
"Based on these results, it was concluded that AOAT1 is targeted to peroxisomes, functions as a photorespiratory GGAT, plays a markedly important role for plant growth and the metabolism of amino acids."
The vegetative vacuole proteome of Arabidopsis thaliana reveals predicted and unexpected proteins.
Glutamate:glyoxylate aminotransferase modulates amino acid content during photorespiration.
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GGAT1 overexpression raises Ser, Gly and citrulline in a light-dependent, CO2-repressible manner; GGAT1 is also expressed in roots.
"The levels of free serine, glycine, and citrulline increased markedly in GGAT1 overexpression lines compared with levels in the wild type"
Altered ABA, proline and hydrogen peroxide in an Arabidopsis glutamate:glyoxylate aminotransferase mutant.
Alanine aminotransferase catalyses the breakdown of alanine after hypoxia in Arabidopsis thaliana.
Proteome analysis of Arabidopsis leaf peroxisomes reveals novel targeting peptides, metabolic pathways, and defense mechanisms.
Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.
Hydroponic isotope labelling of entire plants (HILEP) for quantitative plant proteomics; an oxidative stress case study.
Analysis of the Arabidopsis cytosolic proteome highlights subcellular partitioning of central plant metabolism.
Photorespiration.
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GGAT1 and GGAT2 encode peroxisomal GGATs; ggat1 knockouts have a weak photorespiratory phenotype with residual activity; GGAT1 is also expressed in roots.
"Ggat 1 is not only highly expressed in leaves but also in roots, indicating that its function is not restricted to photorespiration."
A proteomic strategy for global analysis of plant protein complexes.
Global Analysis of Membrane-associated Protein Oligomerization Using Protein Correlation Profiling.
Discovering the RNA-Binding Proteome of Plant Leaves with an Improved RNA Interactome Capture Method.