Gene Ontology annotation through association of InterPro records with GO terms
TreeGrafter-generated GO annotations
Combined Automated Annotation using Multiple IEA Methods
UniProtKB A8W1U0 flat file (Pichia kudriavzevii GPD)
UniProtKB record snapshot for A0A2U9RB90 and the EC 1.1.1.8 proteome search
PAINT IBD nodes for PTHR11728
Cloning and characterization of a NAD+-dependent glycerol-3-phosphate dehydrogenase gene from Candida glycerinogenes, an industrial glycerol producer.
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The cloned 388-residue GPD complements S. cerevisiae gpd1 and gpd1 gpd2 osmosensitive mutants and restores intracellular glycerol accumulation.
"Functional analysis revealed that Saccharomyces cerevisiae gpd1Delta and gpd1Delta/gpd2Delta osmosensitive mutants transformed with CgGPD were restored to the wild-type phenotype when cultured in high osmolarity media, suggesting that it is a functional GPD protein."
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The sequence deposited for this protein is GenBank EU186536, the EMBL record from which UniProtKB A8W1U0 is derived.
"The full-length CgGPD gene sequence including upstream and downstream regions has been deposited in GenBank under accession no. EU186536."
Bio-based oxalic acid production in Issatchenkia orientalis enables sustainable rare earth recovery.
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Deleting GPD in P. kudriavzevii abolishes glycerol byproduct accumulation while the oxalic acid titer is maintained.
"Since glycerol-3-phosphate dehydrogenase (GPD) plays a key role in the glycerol biosynthesis pathway, we knocked out the GPD gene in strain JL01, generating the strain JL02."
GPD1, which encodes glycerol-3-phosphate dehydrogenase, is essential for growth under osmotic stress in Saccharomyces cerevisiae, and its expression is regulated by the high-osmolarity glycerol response pathway.
The two isoenzymes for yeast NAD+-dependent glycerol 3-phosphate dehydrogenase encoded by GPD1 and GPD2 have distinct roles in osmoadaptation and redox regulation.
Dynamic changes in the subcellular distribution of Gpd1p in response to cell stress.
Crystal structures of human glycerol 3-phosphate dehydrogenase 1 (GPD1).