Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
Evidence for a pool of coronin in mammalian cells that is sensitive to PI 3-kinase.
The role of protein kinase C in the transient association of p57, a coronin family actin-binding protein, with phagosomes.
Homotypic dimerization of the actin-binding protein p57/coronin-1 mediated by a leucine zipper motif in the C-terminal region.
Association of the leukocyte plasma membrane with the actin cytoskeleton through coiled coil-mediated trimeric coronin 1 molecules.
Actin-binding proteins coronin-1a and IBA-1 are effective microglial markers for immunohistochemistry.
Coronin function is required for chemotaxis and phagocytosis in human neutrophils.
Lipoamide dehydrogenase mediates retention of coronin-1 on BCG vacuoles, leading to arrest in phagosome maturation.
Defining the membrane proteome of NK cells.
MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.
Toward an understanding of the protein interaction network of the human liver.
Coronin 1C harbours a second actin-binding site that confers co-operative binding to F-actin.
Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
Constitutive turnover of phosphorylation at Thr-412 of human p57/coronin-1 regulates the interaction with actin.
In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.
Lytic immune synapse function requires filamentous actin deconstruction by Coronin 1A.
A proteome-scale map of the human interactome network.
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.
A reference map of the human binary protein interactome.
Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains.
Molecular cloning of a novel actin-binding protein, p57, with a WD repeat and a leucine zipper motif.
Cytosolic phox proteins interact with and regulate the assembly of coronin in neutrophils.
The actin regulator coronin 1A is mutant in a thymic egress-deficient mouse strain and in a patient with severe combined immunodeficiency.
Severe combined immunodeficiency (SCID) and attention deficit hyperactivity disorder (ADHD) associated with a Coronin-1A mutation and a chromosome 16p11.2 deletion.
Whole-exome sequencing identifies Coronin-1A deficiency in 3 siblings with immunodeficiency and EBV-associated B-cell lymphoproliferation.
Reassessment of the roles of coronin proteins as actin effectors and in signaling.
The lupus-related Lmb3 locus contains a disease-suppressing Coronin-1A gene mutation.
The lymphoid lineage-specific actin-uncapping protein Rltpr is essential for costimulation via CD28 and the development of regulatory T cells.
Coronin-1 is a neurotrophin endosomal effector that is required for developmental competition for survival.
Coronin 1 regulates cognition and behavior through modulation of cAMP/protein kinase A signaling.
Coro1a promotes the multivesicular body and plasma membrane fusion by facilitating PKM2-mediated SNAP-23 phosphorylation.
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Human-cell CORO1A perturbation changes extracellular-vesicle output and CD63-pHluorin fusion events, including a baseline knockout effect; much mechanistic dissection uses neddylation inhibition.
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CORO1A coimmunoprecipitates with PKM2 rather than SNAP23. The proposed upstream tyrosine-kinase recruitment mechanism is untested, and the purified lipid-fusion reaction contains SNARE proteins without CORO1A.
CORO1A: short original-source passages
Suppression of caspase 8 activity by a coronin 1-PI3Kδ pathway promotes T cell survival independently of TCR and IL-7 signaling.
Survival of mycobacteria in macrophages is mediated by coronin 1-dependent activation of calcineurin.