GO_REF:0000024
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000044
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
GO_REF:0000052
Gene Ontology annotation based on curation of immunofluorescence data
GO_REF:0000054
Gene Ontology annotation based on curation of intracellular localizations of expressed fusion proteins in living cells
GO_REF:0000104
Electronic Gene Ontology annotations created by transferring manual GO annotations between related proteins based on shared sequence features
GO_REF:0000107
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
GO_REF:0000108
Automatic assignment of GO terms using logical inference, based on on inter-ontology links
GO_REF:0000117
Electronic Gene Ontology annotations created by ARBA machine learning models
GO_REF:0000120
Combined Automated Annotation using Multiple IEA Methods
PMID:16079181
Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins.
PMID:17456799
Sirtuin functions in health and disease.
PMID:18680753
Substrates and regulation mechanisms for the human mitochondrial sirtuins Sirt3 and Sirt5.
PMID:21908771
The first identification of lysine malonylation substrates and its regulatory enzyme.
PMID:22076378
Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase.
PMID:23806337
SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.
PMID:24140062
SIRT5 desuccinylates and activates SOD1 to eliminate ROS.
PMID:24703693
Lysine glutarylation is a protein posttranslational modification regulated by SIRT5.
PMID:29180469
SHMT2 Desuccinylation by SIRT5 Drives Cancer Cell Proliferation.
PMID:34800366
Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context.
Reactome:R-HSA-1592230
Mitochondrial biogenesis
Reactome:R-HSA-5688294
SIRT5 deacetylates Cytochrome C
Reactome:R-HSA-70635
Urea cycle
Reactome:R-HSA-9955504
SIRT5 deglutarylates CPS1
file:human/SIRT5/SIRT5-uniprot.txt
UniProt record for human SIRT5