Gene Ontology annotation through association of InterPro records with GO terms
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Electronic Gene Ontology annotations created by ARBA machine learning models
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Combined Automated Annotation using Multiple IEA Methods
The membrane IgM-associated proteins MB-1 and Ig-beta are sufficient to promote surface expression of a partially functional B-cell antigen receptor in a nonlymphoid cell line.
Structural and functional studies of Igalphabeta and its assembly with the B cell antigen receptor.
Impact of lactobacilli on orally acquired listeriosis.
Reconstitution of B cell antigen receptor-induced signaling events in a nonlymphoid cell line by expressing the Syk protein-tyrosine kinase.
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Active Syk restores several BCR outputs in AtT20 reconstitution, but not inositol-phosphate production.
"Syk expression did not reconstitute anti-IgM-induced
inositol phosphate production."
Phosphorylation of ITAMs of Ig-alpha (Cd79a) and Ig-beta (Cd79b)
The B cell antigen receptor complex: association of Ig-alpha and Ig-beta with distinct cytoplasmic effectors.
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The two CD79 cytoplasmic tails associate with distinct sets of signaling effectors.
"The cytoplasmic tails of
Ig-alpha and Ig-beta chains were found to associate with distinct sets of
effector molecules."
B cell progenitors are arrested in maturation but have intact VDJ recombination in the absence of Ig-alpha and Ig-beta.
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Native mouse Cd79a/Cd79b loss blocks developmental progression without abolishing V(D)J recombination.
"neither in Ig-alpha- nor in Ig-beta-deficient mice are pro-B cells impaired in
V(D)J recombination"
Interference with immunoglobulin (Ig)alpha immunoreceptor tyrosine-based activation motif (ITAM) phosphorylation modulates or blocks B cell development, depending on the availability of an Igbeta cytoplasmic tail.
Homooligomerization of the cytoplasmic domain of the T cell receptor zeta chain and of other proteins containing the immunoreceptor tyrosine-based activation motif.
The membrane IgM-associated proteins MB-1 and Ig-beta are sufficient to promote surface expression of a partially functional B-cell antigen receptor in a nonlymphoid cell line