Gene Ontology annotation through association of InterPro records with GO terms
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Gene Ontology annotation of human sequence-specific DNA binding transcription factors (DbTFs) based on the TFClass database
Combined Automated Annotation using Multiple IEA Methods
Novel TFAP2B mutations that cause Char syndrome provide a genotype-phenotype correlation.
Cardiac malformations, adrenal agenesis, neural crest defects and exencephaly in mice lacking Cited2, a new Tfap2 co-activator.
Transcription factor AP-2 interacts with the SUMO-conjugating enzyme UBC9 and is sumolated in vivo.
The role of Sp1 and AP-2 in basal and protein kinase A--induced expression of mitochondrial serine:pyruvate aminotransferase in hepatocytes.
Physical and functional interactions among AP-2 transcription factors, p300/CREB-binding protein, and CITED2.
Genetic variations in the gene encoding TFAP2B are associated with type 2 diabetes mellitus.
Intronic polymorphisms within TFAP2B regulate transcriptional activity and affect adipocytokine gene expression in differentiated adipocytes.
Comparative expression profiling identifies an in vivo target gene signature with TFAP2B as a mediator of the survival function of PAX3/FKHR.
The interaction of KCTD1 with transcription factor AP-2alpha inhibits its transactivation.
The transcription factor TFAP2B is associated with insulin resistance and adiposity in healthy adolescents.
AP2 transcription factor induces apoptosis in retinoblastoma cells.
Impact of cytosine methylation on DNA binding specificities of human transcription factors.
Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains.
Cloning and characterization of a second AP-2 transcription factor: AP-2 beta.
Transcription factor AP-2 regulates human insulin-like growth factor binding protein-5 gene expression.
Chromosomal mapping of the human and mouse homologues of two new members of the AP-2 family of transcription factors.
AP-2 (TFAP2) transcription factors form homo- and heterodimers
TFAP2 homo- and heterodimers bind CITED and EP300/CREBBP
KCTD1 binds TFAP2 homo- and heterodimers
TFAP2B homodimer binds YEATS4
Deep research report on TFAP2B (Falcon)
An alternatively spliced mRNA from the AP-2 gene encodes a negative regulator of transcriptional activation by AP-2.
Enhanced apoptotic cell death of renal epithelial cells in mice lacking transcription factor AP-2beta.
Mutations in TFAP2B cause Char syndrome, a familial form of patent ductus arteriosus.
Terminal renal failure in mice lacking transcription factor AP-2 beta.
Transcriptional regulation during development of the ductus arteriosus.
The transcription factors AP-2β and AP-2α are required for survival of sympathetic progenitors and differentiated sympathetic neurons.
A heart-hand syndrome gene: Tfap2b plays a critical role in the development and remodeling of mouse ductus arteriosus and limb patterning.
Transcription factor activating protein 2 beta (TFAP2B) mediates noradrenergic neuronal differentiation in neuroblastoma.
Comparative analysis of AP-2 alpha and AP-2 beta gene expression during murine embryogenesis.
AP-2α and AP-2β cooperatively function in the craniofacial surface ectoderm to regulate chromatin and gene expression dynamics during facial development.
TFAP2B Haploinsufficiency Impacts Gastrointestinal Function and Leads to Pediatric Intestinal Pseudo-obstruction.
AP2-dependent signals from the ectoderm regulate craniofacial development in the zebrafish embryo.
Heterodimerization of TFAP2 pioneer factors drives epigenomic remodeling during neural crest specification.
Pax3 and Zic1 trigger the early neural crest gene regulatory network by the direct activation of multiple key neural crest specifiers.
Reprogramming of avian neural crest axial identity and cell fate.
Evolution of the new head by gradual acquisition of neural crest regulatory circuits.