GO_REF:0000002

Gene Ontology annotation through association of InterPro records with GO terms

GO_REF:0000118

TreeGrafter-generated GO annotations

GO_REF:0000120

Combined Automated Annotation using Multiple IEA Methods

file:PSEPK/prs/prs-uniprot.txt

UniProtKB reviewed entry for prs (Q88PX6)

"Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate"
"SUBUNIT: Homohexamer"

file:PSEPK/prs/prs-goa.tsv

QuickGO GOA annotations for prs

file:interpro/panther/PTHR10210/PTHR10210-metadata.yaml

PANTHER family metadata for prs

file:PSEPK/prs/prs-deep-research-falcon.md

Falcon deep research report on prs (Q88PX6)

"catalyzes the formation of PRPP from ribose-5-phosphate and ATP, producing AMP"
"irreversible diphosphoryl transfer from ATP to ribose-5-phosphate"
"PRPP is a central "activated ribose" donor"
"supplies ribose-phosphate to multiple biosynthetic pathways"
"PRPP is broadly required for"
"Purine and pyrimidine nucleotide biosynthesis"
"NAD and NADP"
"histidine and tryptophan"
"class I enzymes require divalent cations, including"
"phosphate (Pi)-activated"
"AMP, ADP, and GDP"
"soluble cytosolic enzyme"
"filamentous assemblies (cytoophidia)"
"resistant to allosteric inhibition"
"essential for free-living organisms"
"ribose-phosphate pyrophosphokinase family"