AKT2 review notes
Deep research via falcon/perplexity-lite failed (no provider keys); research from cached publications and UniProt.
- Ser/Thr kinase, kinetics PMID:16540465
- Insulin-specific role in human muscle PMID:16814735; lipid metabolism attributed to Akt1 in abstract PMID:16814735 -> lipid IMP rows UNDECIDED.
- Substrate PKP1 PMID:23444369
- Localization: cytosolic soluble kinase; PH domain recruits to PM inner leaflet (UniProt, by similarity: "Through binding of the N-terminal PH domain to phosphatidylinositol (3,4,5)-trisphosphate ... recruited to the plasma membrane."); nuclear pool in myoblasts PMID:17565718; nuclear degradation via TTC3 PMID:20059950. Not a cell-surface (extracellular-exposed) protein.
- Protein binding rows (24) removed per policy.
- "molecular function activator activity" EXP from crystal structure paper PMID:12517337: UNDECIDED (no supporting content in abstract).