Centriole distal appendages promote membrane docking, leading to cilia initiation.

CCDC41 is required for ciliary vesicle docking to the mother centriole.

Super-resolution architecture of mammalian centriole distal appendages reveals distinct blade and matrix functional components.

Phosphorylation of CEP83 by TTBK2 is necessary for cilia initiation.

Centrosome anchoring regulates progenitor properties and cortical formation.

Mutations of CEP83 cause infantile nephronophthisis and intellectual disability.

Deep research report on CEP83 (falcon)

Intrinsic heterogeneity of primary cilia revealed through spatial proteomics.

Annotation inferences using phylogenetic trees

Combined Automated Annotation using Multiple IEA Methods

RAB3IP stimulates nucleotide exchange on RAB8A

C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole

CP110 and CEP97 dissociate from the centriole

The distal appendage proteins recruit TTBK2

Recruitment of transition zone proteins

MARK4 binds ODF2 in the centriole

CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body