Gene Ontology annotation through association of InterPro records with GO terms
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Gene Ontology annotations Inferred by Curator (IC) using at least one Inferred by Sequence Similarity (ISS) annotation to support the inference
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
Clathrin assembly lymphoid myeloid leukemia (CALM) protein: localization in endocytic-coated pits, interactions with clathrin, and the impact of overexpression on clathrin-mediated traffic.
Nucleocytoplasmic shuttling of endocytic proteins.
Analysis of clathrin-mediated endocytosis of epidermal growth factor receptor by RNA interference.
Effect of clathrin assembly lymphoid myeloid leukemia protein depletion on clathrin coat formation.
The novel CALM interactor CATS influences the subcellular localization of the leukemogenic fusion protein CALM/AF10.
Evidence for CALM in directing VAMP2 trafficking.
Defining the membrane proteome of NK cells.
CALM, a clathrin assembly protein, influences cell surface GluR2 abundance.
The molecular basis for the endocytosis of small R-SNAREs by the clathrin adaptor CALM.
FHL2 interacts with CALM and is highly expressed in acute erythroid leukemia.
The PICALM protein plays a key role in iron homeostasis and cell proliferation.
A high-confidence interaction map identifies SIRT1 as a mediator of acetylation of USP22 and the SAGA coactivator complex.
Clathrin adaptor CALM/PICALM is associated with neurofibrillary tangles and is cleaved in Alzheimer's brains.
Decreased CALM expression reduces Aβ42 to total Aβ ratio through clathrin-mediated endocytosis of γ-secretase.
E-cadherin interactome complexity and robustness resolved by quantitative proteomics.
CALM regulates clathrin-coated vesicle size and maturation by directly sensing and driving membrane curvature.
Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance.
A human interactome in three quantitative dimensions organized by stoichiometries and abundances.
Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.
The t(10;11)(p13;q14) in the U937 cell line results in the fusion of the AF10 gene and CALM, encoding a new member of the AP-3 clathrin assembly protein family.
F- and N- BAR domain proteins bind the clathrin-coated pit
CLASP proteins and cargo are recruited to the nascent clathrin-coated pit
Clathrin recruits PIK3C2A
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2
SNX9 recruits components of the actin polymerizing machinery
BAR domain proteins recruit dynamin
SYNJ hydrolyze PI(4,5)P2 to PI(4)P
Endophilins recruit synaptojanins to the clathrin-coated pit
HSPA8-mediated ATP hydrolysis promotes vesicle uncoating
Clathrin recruits auxilins to the clathrin-coated vesicle
Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle
Dynamin-mediated GTP hydrolysis promotes vesicle scission
Dissociation of clathrin-associated proteins
Dissociation of AAK1 and dephosphorylation of AP-2 mu2
RAB5 and GAPVD1 bind AP-2