TSC3 (Q3E790, YBR058C-A) notes

Module: sphingolipid_de_novo_synthesis, fungal Tsc3 SPT small-subunit variant (enzyme activator). Not in YeastCyc SPHINGOLIPID-SYN-PWY-1 gene list.

Evidence journal

• SPT activity PMID:10713067
• Association PMID:10713067
• SPOTS PMID:20182505
• C20-LCBs PMID:23286903
• ER membrane [UniProt:Q3E790]

Decisions

• All rows ACCEPT except sphingolipid homeostasis NAS (KEEP_AS_NON_CORE; homeostasis executed by Orm1/2).