Gene Ontology annotation through association of InterPro records with GO terms
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping
A role for Mediator complex subunit MED13L in Rb/E2F-induced growth arrest.
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MED13L is required for Rb/E2F control of cell growth and cell cycle gene regulation
"the Mediator complex subunit MED13L is required for Rb/E2F control of cell growth, the complete repression of cell cycle target genes, and cell cycle inhibition"
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Mediator complex is a multiprotein coactivator required for Pol II transcription
"components of the Mediator complex, a large multiprotein coactivator required for RNA polymerase II transcription"
NS1 (1C) binds to Mediator complex
Deep research review of MED13L function
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MED13L functions as a CKM tether with Ago-like domain architecture
"MED13L encodes Mediator of RNA polymerase II transcription subunit 13-like, a non-enzymatic subunit of the Mediator complex's cyclin-dependent kinase module (CKM)"
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MED13L is required for neuronal dendritic development
"MED13L is required for dendritic development of cortical excitatory neurons; disease-associated variants impact subcellular distribution/stability and reduce dendrite number/length or spine maturation"