Gene Ontology annotation through association of InterPro records with GO terms
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Automatic assignment of GO terms using logical inference, based on on inter-ontology links
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
Ultrastructural distribution of 36-kD microfibril-associated glycoprotein (MAGP-36) in human and bovine tissues.
Interactions of fibrillin-1 with heparin/heparan sulfate, implications for microfibrillar assembly.
Assembly of epithelial cell fibrillins.
Latent transforming growth factor beta-binding protein 1 interacts with fibrillin and is a microfibril-associated protein.
Cell adhesion to fibrillin-1 molecules and microfibrils is mediated by alpha 5 beta 1 and alpha v beta 3 integrins.
Structure of the integrin binding fragment from fibrillin-1 gives new insights into microfibril organization.
MAGP-2 has multiple binding regions on fibrillins and has covalent periodic association with fibrillin-containing microfibrils.
Molecular structure and interaction of recombinant human type XVI collagen.
Microfibrils at basement membrane zones interact with perlecan via fibrillin-1.
Treatment of aortic disease in patients with Marfan syndrome.
Fibulin-5 interacts with fibrillin-1 molecules and microfibrils.
alphaVbeta6 is a novel receptor for human fibrillin-1. Comparative studies of molecular determinants underlying integrin-rgd affinity and specificity.
LTBP-2 specifically interacts with the amino-terminal region of fibrillin-1 and competes with LTBP-1 for binding to this microfibrillar protein.
Targeting of bone morphogenetic protein growth factor complexes to fibrillin.
Biogenesis of extracellular microfibrils: Multimerization of the fibrillin-1 C terminus into bead-like structures enables self-assembly.
Purification and partial characterization of fibrillin, a cysteine-rich structural component of connective tissue microfibrils.
Latent transforming growth factor beta-binding proteins and fibulins compete for fibrillin-1 and exhibit exquisite specificities in binding sites.
Differential regulation of elastic fiber formation by fibulin-4 and -5.
Antagonistic effect of the matricellular signaling protein CCN3 on TGF-beta- and Wnt-mediated fibrillinogenesis in systemic sclerosis and Marfan syndrome.
Proteomics characterization of extracellular space components in the human aorta.
ADAMTS10 protein interacts with fibrillin-1 and promotes its deposition in extracellular matrix of cultured fibroblasts.
Essential role of microfibrillar-associated protein 4 in human cutaneous homeostasis and in its photoprotection.
Comparative proteomic analysis of supportive and unsupportive extracellular matrix substrates for human embryonic stem cell maintenance.
SILAC-based proteomics of human primary endothelial cell morphogenesis unveils tumor angiogenic markers.
Structure of the fibrillin-1 N-terminal domains suggests that heparan sulfate regulates the early stages of microfibril assembly.
Fibrillin-1 directly regulates osteoclast formation and function by a dual mechanism.
C-terminal propeptide is required for fibrillin-1 secretion and blocks premature assembly through linkage to domains cbEGF41-43.
Heparin/heparan sulfate controls fibrillin-1, -2 and -3 self-interactions in microfibril assembly.
Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.
Human eye development is characterized by coordinated expression of fibrillin isoforms.
Characterization of Microfibrillar-associated Protein 4 (MFAP4) as a Tropoelastin- and Fibrillin-binding Protein Involved in Elastic Fiber Formation.
Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.
Asprosin, a Fasting-Induced Glucogenic Protein Hormone.
Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation.
Comprehensive proteomic characterization of stem cell-derived extracellular matrices.
Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.
OLFR734 Mediates Glucose Metabolism as a Receptor of Asprosin.
A reference map of the human binary protein interactome.
POGLUT2 and POGLUT3 O-glucosylate multiple EGF repeats in fibrillin-1, -2, and LTBP1 and promote secretion of fibrillin-1.
Fibrillin, a new 350-kD glycoprotein, is a component of extracellular microfibrils.
MatrisomeDB 2.0: 2023 updates to the ECM-protein knowledge database.
The association of human fibulin-1 with elastic fibers: an immunohistological, ultrastructural, and RNA study.
Fibrillin binds calcium and is coded by cDNAs that reveal a multidomain structure and alternatively spliced exons at the 5' end.
Structure and expression of fibrillin-2, a novel microfibrillar component preferentially located in elastic matrices.
A novel mutation of the fibrillin gene causing ectopia lentis.
Fibulin binds elastic fibres
Tropoelastin associates with microfibrils
Fibrillin C-terminal processing
Fibrillin microfibril assembly
Elastin cross-linking by lysyl oxidase
MFAP2, MFAP5 bind microfibrils
Elastic fibres bind associated proteins
Fibrillin-1 binds latent TGF-beta
Fibrillin-1 binds integrins
Fibrillin 1, 2,(3) degradation by MMP2, 9, 12 and 13
Fibrillin-1 degradation by MMP3, CTSK, CTSL2
Fibrillin-1 degradation by MMP14
Interaction of integrin alphaVbeta3 with Fibrillin
FAM20C phosphorylates FAM20C substrates
Ptprf is the conserved receptor for Asprosin's glucogenic effects in vertebrates.
Case Reports of Pre-clinical Replication Studies in Metabolism and Diabetes.
Elastic fiber proteins in the glomerular mesangium in vivo and in cell culture.
Endothelial dysfunction in murine model of systemic sclerosis: tight-skin mice 1.
Fibulin-2 and fibulin-5 alterations in tsk mice associated with disorganized hypodermal elastic fibers and skin tethering.
Early emphysema in the tight skin and pallid mice: roles of microfibril-associated glycoproteins, collagen, and mechanical forces.
Decorin-mediated regulation of fibrillin-1 in the kidney involves the insulin-like growth factor-I receptor and Mammalian target of rapamycin.
Effects of D-4F on vasodilation, oxidative stress, angiostatin, myocardial inflammation, and angiogenic potential in tight-skin mice.
BAFF antagonist attenuates the development of skin fibrosis in tight-skin mice.
Fibrillin-1 and -2 differentially modulate endogenous TGF-β and BMP bioavailability during bone formation.
Asprosin is a centrally acting orexigenic hormone.
Targeting of cadherin-11 decreases skin fibrosis in the tight skin-1 mouse model.
Isolation of rat fibrillin-1 cDNA and its relevance in metanephric development.
Initial steps in assembly of microfibrils. Formation of disulfide-cross-linked multimers containing fibrillin-1.