Gene Ontology annotation through association of InterPro records with GO terms
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Combined Automated Annotation using Multiple IEA Methods
Phosphoenolpyruvate carboxykinase is necessary for the integration of hepatic energy metabolism.
A mutation in the peroxisome proliferator-activated receptor gamma-binding site in the gene for the cytosolic form of phosphoenolpyruvate carboxykinase reduces adipose tissue size and fat content in mice.
The roles of ATF3 in liver dysfunction and the regulation of phosphoenolpyruvate carboxykinase gene expression.
Impaired tricarboxylic acid cycle activity in mouse livers lacking cytosolic phosphoenolpyruvate carboxykinase.
Potassium restriction, high protein intake, and metabolic acidosis increase expression of the glutamine transporter SNAT3 (Slc38a3) in mouse kidney.
HIF-1alpha is necessary to support gluconeogenesis during liver regeneration.
Impact of lactobacilli on orally acquired listeriosis.
A Pck1-directed glycogen metabolic program regulates formation and maintenance of memory CD8(+) T cells.
Dynamic Acetylation of Phosphoenolpyruvate Carboxykinase Toggles Enzyme Activity between Gluconeogenic and Anaplerotic Reactions.
Multitissue 2H/13C flux analysis reveals reciprocal upregulation of renal gluconeogenesis in hepatic PEPCK-C-knockout mice.
Pck1 gene expression is stimulated by Foxo1:Ppargc1a
The gluconeogenic enzyme PCK1 phosphorylates INSIG1/2 for lipogenesis.
Porcine reproductive and respiratory syndrome virus activates lipid synthesis through a ROS-dependent AKT/PCK1/INSIG/SREBPs axis.
Overexpression of the cytosolic form of phosphoenolpyruvate carboxykinase (GTP) in skeletal muscle repatterns energy metabolism in the mouse.
Increased fatty acid re-esterification by PEPCK overexpression in adipose tissue leads to obesity without insulin resistance.
What is the metabolic role of phosphoenolpyruvate carboxykinase?
PCK1 is a key regulator of metabolic and mitochondrial functions in renal tubular cells.
UniProt entry Q9Z2V4 (PCK1_MOUSE)
GO-CAM gomodel:6205c24300000880 Regulation of cholesterol biosynthesis by SREBP (SREBF1 and SREBF2) and retention by the SREBP-SCAP complex (Human)
Glucocorticoids regulate transcription of the gene for phosphoenolpyruvate carboxykinase in the liver via an extended glucocorticoid regulatory unit.