BMP-2 and BMP-9 promotes chondrogenic differentiation of human multipotential mesenchymal cells and overcomes the inhibitory effect of IL-1.
Osteogenic activity of the fourteen types of human bone morphogenetic proteins (BMPs).
The DNA sequence and comparative analysis of human chromosome 10.
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Crystal structure of BMP-9 and functional interactions with pro-region and receptors.
Bone morphogenetic proteins 2, 4, and 9 stimulate murine hepcidin 1 expression independently of Hfe, transferrin receptor 2 (Tfr2), and IL-6.
Identification of BMP9 and BMP10 as functional activators of the orphan activin receptor-like kinase 1 (ALK1) in endothelial cells.
Bone morphogenetic protein-9 is a circulating vascular quiescence factor.
Large-scale proteomics and phosphoproteomics of urinary exosomes.
Bone morphogenetic protein (BMP) and activin type II receptors balance BMP9 signals mediated by activin receptor-like kinase-1 in human pulmonary artery endothelial cells.
ALK1 signaling regulates early postnatal lymphatic vessel development.
Mutations in GDF5 reveal a key residue mediating BMP inhibition by NOGGIN.
BMP-9 induces proliferation of multiple types of endothelial cells in vitro and in vivo.
TGFbeta/BMP type I receptors ALK1 and ALK2 are essential for BMP9-induced osteogenic signaling in mesenchymal stem cells.
BMP9 is produced by hepatocytes and circulates mainly in an active mature form complexed to its prodomain.
Soluble endoglin specifically binds bone morphogenetic proteins 9 and 10 via its orphan domain, inhibits blood vessel formation, and suppresses tumor growth.
Structural and functional insights into endoglin ligand recognition and binding.
Specificity and structure of a high affinity activin receptor-like kinase 1 (ALK1) signaling complex.
Structure of the Alk1 extracellular domain and characterization of its bone morphogenetic protein (BMP) binding properties.
Endoglin requirement for BMP9 signaling in endothelial cells reveals new mechanism of action for selective anti-endoglin antibodies.
BMP9 mutations cause a vascular-anomaly syndrome with phenotypic overlap with hereditary hemorrhagic telangiectasia.
Regulation of bone morphogenetic protein 9 (BMP9) by redox-dependent proteolysis.
Structure of bone morphogenetic protein 9 procomplex.
Structural Basis of the Human Endoglin-BMP9 Interaction: Insights into BMP Signaling and HHT1.
MiR-199b-5p Suppresses Tumor Angiogenesis Mediated by Vascular Endothelial Cells in Breast Cancer by Targeting ALK1.
Decreased Colonic Activin Receptor-Like Kinase 1 Disrupts Epithelial Barrier Integrity in Patients With Crohn's Disease.
GDF2 and BMP10 coordinate liver cellular crosstalk to maintain liver health.
Bone morphogenetic protein-9 binds to liver cells and stimulates proliferation.
Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
UniProtKB Q9UK05: Growth/differentiation factor 2
GDF2 source scope, products, phylogeny and context projection