pvdT (PA2390, Q9I190) review notes

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PvdRT-OpmQ is a tripartite MacB-type ABC exporter PMID:19906986.
Periplasmic accumulation in mutants PMID:19906986.
Secretion of new PVD PMID:21035449; recycling PMID:23766114; metal-complex export PMID:22187978.
PMID:12686626 (pyoverdine biosynthesis row): mutant screen scored by pyoverdine production PMID:12686626. Abstract only.

PseudoCAP IBA-seed assessment

PTN node	node term	n_seeds	leaf IBAs	seed annotation (term, evidence, PMID)	other seeds	IBD stands without this seed?	verdict	rationale
PTN001254814	GO:0022857 transmembrane transporter activity	2	118 (36 taxa)	GO:0015562, IDA/IMP, PMID:19906986, PMID:21035449, PMID:22187978, PMID:23766114 (PseudoCAP)	E. coli MacB P75831	Yes (MacB is an experimentally characterized ABC exporter)	SOUND	Mutants of any pump component trap pyoverdine in the periplasm; PvdT is the energizing IM component. Generic node term suits a MacB-like clade exporting different substrates.

Shared nodes: pvdR (membrane fusion protein) and opmQ (outer membrane factor) belong to other PANTHER families and do not share PTN001254814, so no node-level defect is shared.

Defects: PSEUDOCAP WRONG_TERM on GO:0002049 pyoverdine biosynthetic process (PROBABLE; indirect phenotype, row does not seed a worklist IBD). No GO_CENTRAL defect.