GO_REF:0000118

TreeGrafter-generated GO annotations

GO_REF:0000120

Combined Automated Annotation using Multiple IEA Methods

file:PSEPK/moaB-I/moaB-I-uniprot.txt

UniProtKB entry for moaB-I

UniProt places Q88L15 in the proteobacterial MoaB family and transfers GTP/MPT binding but no MPT adenylyltransferase activity.

"CC -!- FUNCTION: May be involved in the biosynthesis of molybdopterin. Can CC bind GTP and has low GTPase activity. Can bind MPT, but has no MPT CC adenylyl transferase activity. {ECO:0000256|ARBA:ARBA00055616}."

file:PSEPK/moaB-I/moaB-I-goa.tsv

QuickGO GOA annotations for moaB-I

The fetched table contains the cytosol and Mo-molybdopterin biosynthesis rows reviewed here.

"UniProtKB Q88L15 moaB-I located_in GO:0005829 cytosol cellular_component ECO:0007826 IEA GO_REF:0000118 PANTHER:PTN002456466 160488 Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) TreeGrafter Molybdenum cofactor biosynthesis protein B 20260706 UniProtKB Q88L15 moaB-I involved_in GO:0006777 Mo-molybdopterin cofactor biosynthetic process biological_process ECO:0000501 IEA GO_REF:0000120 InterPro:IPR008284|InterPro:IPR012245|InterPro:IPR013484|UniRule:UR000143783 160488 Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) UniProt Molybdenum cofactor biosynthesis protein B 20260706"

file:PSEPK/moaB-I/moaB-I-deep-research-openscientist.md

OpenScientist gene research for moaB-I

The report explicitly acknowledges that neither the target protein nor the distinct physiological role of MoaB has been resolved experimentally.

"2. **MoaB's precise physiological role is unresolved even in *E. coli*.** Despite two crystal structures, the specific in vivo activity of MoaB (as distinct from MogA) has never been unambiguously established."

file:interpro/panther/PTHR43232/PTHR43232-entries.csv

PANTHER entries for the MoaB family

PTHR43232 contains MoaB proteins, including biochemically active archaeal MoaB, but does not by itself resolve each bacterial paralog.

"Q8U3T3,Molybdopterin adenylyltransferase,protein,186497,Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1),Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1),moaB,169,PTHR43232:SF2,MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN B,True"