Gene Ontology annotation through association of InterPro records with GO terms

Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity

Annotation inferences using phylogenetic trees

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara

Electronic Gene Ontology annotations created by ARBA machine learning models

Combined Automated Annotation using Multiple IEA Methods

The neuronal form of adaptor protein-3 is required for synaptic vesicle formation from endosomes.

Localization of the AP-3 adaptor complex defines a novel endosomal exit site for lysosomal membrane proteins.

Gravity receptor function in mice with graded otoconial deficiencies.

Genetic analysis of the neuronal and ubiquitous AP-3 adaptor complexes reveals divergent functions in brain.

AP-1 and AP-3 facilitate lysosomal targeting of Batten disease protein CLN3 via its dileucine motif.

Vglut1 and ZnT3 co-targeting mechanisms regulate vesicular zinc stores in PC12 cells.

Functions of adaptor protein (AP)-3 and AP-1 in tyrosinase sorting from endosomes to melanosomes.

BLOC-1 complex deficiency alters the targeting of adaptor protein complex-3 cargoes.

Zinc transporter 2 (SLC30A2) can suppress the vesicular zinc defect of adaptor protein 3-depleted fibroblasts by promoting zinc accumulation in lysosomes.

The subcellular localization of the Niemann-Pick Type C proteins depends on the adaptor complex AP-3.

Integral and associated lysosomal membrane proteins.

Sorting of the v-SNARE VAMP7 in Dictyostelium discoideum: a role for more than one Adaptor Protein (AP) complex.

Hermansky-Pudlak syndrome protein complexes associate with phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells.

Roles of BLOC-1 and adaptor protein-3 complexes in cargo sorting to synaptic vesicles.

Defining the membrane proteome of NK cells.

Hermansky-Pudlak protein complexes, AP-3 and BLOC-1, differentially regulate presynaptic composition in the striatum and hippocampus.

The schizophrenia susceptibility factor dysbindin and its associated complex sort cargoes from cell bodies to the synapse.

BLOC-2, AP-3, and AP-1 proteins function in concert with Rab38 and Rab32 proteins to mediate protein trafficking to lysosome-related organelles.

Structural basis of the intracellular sorting of the SNARE VAMP7 by the AP3 adaptor complex.

Adaptor protein complexes 1 and 3 are essential for generation of synaptic vesicles from activity-dependent bulk endosomes.

Cell type-specific Rab32 and Rab38 cooperate with the ubiquitous lysosome biogenesis machinery to synthesize specialized lysosome-related organelles.

Chemical-genetic disruption of clathrin function spares adaptor complex 3-dependent endosome vesicle biogenesis.

Stargazin regulates AMPA receptor trafficking through adaptor protein complexes during long-term depression.

Mutations in AP3D1 associated with immunodeficiency and seizures define a new type of Hermansky-Pudlak syndrome.

Biallelic mutations in AP3D1 cause Hermansky-Pudlak syndrome type 10 associated with immunodeficiency and seizure disorder.

Adaptor protein-3 complex is required for Vangl2 trafficking and planar cell polarity of the inner ear.

A BLOC-1-AP-3 super-complex sorts a cis-SNARE complex into endosome-derived tubular transport carriers.

A homozygous AP3D1 missense variant in patients with sensorineural hearing loss as the leading manifestation.

A structure-based mechanism for initiation of AP-3 coated vesicle formation.

Architecture of clathrin-independent AP3:ARF1-coated carriers.

Characterization of the adaptor-related protein complex, AP-3.

Suppressors of YCK-encoded yeast casein kinase 1 deficiency define the four subunits of a novel clathrin AP-like complex.

Altered expression of a novel adaptin leads to defective pigment granule biogenesis in the Drosophila eye color mutant garnet.

The AP-3 adaptor complex is essential for cargo-selective transport to the yeast vacuole.

Association of the AP-3 adaptor complex with clathrin.

ADP-Ribosylation factor 1 (ARF1) regulates recruitment of the AP-3 adaptor complex to membranes.

Mutation in AP-3 delta in the mocha mouse links endosomal transport to storage deficiency in platelets, melanosomes, and synaptic vesicles.

AP3D1 bioinformatics: delta-adaptin interface conservation and GOA reconciliation

Affinage mechanistic annotation for AP3D1 (human)

UniProt entry O14617 (AP3D1_HUMAN)