CTA1 notes (YDR256C, P15202)

• Peroxisomal catalase A, heme catalase, homotetramer [UniProt:P15202 "SUBCELLULAR LOCATION: Peroxisome matrix"]; PTS1 C-terminal SKF.
• Structure/activity: PMID:9931255
• Genetics: PMID:3897793; glucose-repressed.
• Dual targeting: PMID:14998369
• Peroxisome import: PMID:1986244
• Catalase double mutant: PMID:15893481

Curation observations

• RCA cytosol (DETOX1-PWY) REMOVED: Cta1 is peroxisomal/mitochondrial; Ctt1 is the cytosolic catalase.
• RCA removal of superoxide radicals REMOVED: DETOX1-PWY "superoxide radicals degradation" superpathway inflation; catalase acts on H2O2.
• RSP5 protein binding (HTP WW screen) REMOVED per protein-binding policy.