DPH6 (YLR143W, Q12429) notes

Module diphthamide_biosynthesis, step 4 (EC 6.3.1.14). Absent from YeastCyc PWY-6482-1 (YeastCyc gives this reaction to RRT2).

• Diphthamide synthetase PMID:23169644; in vitro with NH4+ not glutamine, AMP product PMID:23169644.
• Human ATPBD4 complements PMID:23169644.
• dph6 accumulates diphthine; ATP-binding domain essential; binds eEF2 PMID:23468660.
• Cytoplasmic [PMID:14562095; UniProt:Q12429].

Observations: all 11 GOA rows accepted. Gene product is missing from the YeastPathways GO-CAM; it should enable GO:0017178 there instead of RRT2.