Gene Ontology annotation through association of InterPro records with GO terms
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Automatic assignment of GO terms using logical inference, based on on inter-ontology links
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
Driving AMPA receptors into synapses by LTP and CaMKII: requirement for GluR1 and PDZ domain interaction.
Targeting of PKA to glutamate receptors through a MAGUK-AKAP complex.
Mutagenesis reveals a role for ABP/GRIP binding to GluR2 in synaptic surface accumulation of the AMPA receptor.
Distinct molecular mechanisms and divergent endocytotic pathways of AMPA receptor internalization.
Subunit-specific rules governing AMPA receptor trafficking to synapses in hippocampal pyramidal neurons.
Conditional restoration of hippocampal synaptic potentiation in Glur-A-deficient mice.
Voltage and concentration dependence of Ca(2+) permeability in recombinant glutamate receptor subtypes.
Control of synaptic strength by glial TNFalpha.
Alpha7 nicotinic acetylcholine receptors occur at postsynaptic densities of AMPA receptor-positive and -negative excitatory synapses in rat sensory cortex.
D1 dopamine receptor stimulation increases GluR1 surface expression in nucleus accumbens neurons.
PKA phosphorylation of AMPA receptor subunits controls synaptic trafficking underlying plasticity.
Molecular cloning, chromosomal mapping, and functional expression of human brain glutamate receptors.
The human glutamate receptor cDNA GluR1: cloning, sequencing, expression and localization to chromosome 5.
Brain-derived neurotrophic factor signal enhances and maintains the expression of AMPA receptor-associated PDZ proteins in developing cortical neurons.
Complete sequencing and characterization of 21,243 full-length human cDNAs.
Modulation of synaptic plasticity by antimanic agents: the role of AMPA glutamate receptor subunit 1 synaptic expression.
The DNA sequence and comparative analysis of human chromosome 5.
Actin/alpha-actinin-dependent transport of AMPA receptors in dendritic spines: role of the PDZ-LIM protein RIL.
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
A single high dose of cocaine induces behavioural sensitization and modifies mRNA encoding GluR1 and GAP-43 in rats.
Impaired synaptic function in the microglial KARAP/DAP12-deficient mouse.
Presynaptic localization of an AMPA-type glutamate receptor in corticostriatal and thalamostriatal axon terminals.
Involvement of myosin Vb in glutamate receptor trafficking.
Molecular cloning and chromosomal localization of one of the human glutamate receptor genes.
Direct interaction of post-synaptic density-95/Dlg/ZO-1 domain-containing synaptic molecule Shank3 with GluR1 alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor.
Peptide binding and NMR analysis of the interaction between SAP97 PDZ2 and GluR-A: potential involvement of a disulfide bond.
Ultrastructural localisation and differential agonist-induced regulation of AMPA and kainate receptors present at the presynaptic active zone and postsynaptic density.
Ca2+ permeability of KA-AMPA--gated glutamate receptor channels depends on subunit composition.
Neuronal proteins involved in synaptic targeting of AMPA receptors in rat hippocampus by antidepressant drugs.
LTP inhibits LTD in the hippocampus via regulation of GSK3beta.
The cell biology of synaptic plasticity: AMPA receptor trafficking.
Functional proteomics identify cornichon proteins as auxiliary subunits of AMPA receptors.
The potential role of phrenic nucleus glutamate receptor subunits in mediating spontaneous crossed phrenic activity in neonatal rat.
Crystal structure and association behaviour of the GluR2 amino-terminal domain.
BDNF activates mTOR to regulate GluR1 expression required for memory formation.
Long-term exposure to endogenous levels of tributyltin decreases GluR2 expression and increases neuronal vulnerability to glutamate.
Estrogen receptor alpha and beta specific agonists regulate expression of synaptic proteins in rat hippocampus.
Nucleus accumbens neurons exhibit synaptic scaling that is occluded by repeated dopamine pre-exposure.
Neuroligin-1 performs neurexin-dependent and neurexin-independent functions in synapse validation.
Fast, quantitative in situ hybridization of rare mRNAs using 14C-standards and phosphorus imaging.
Early exposure of cultured hippocampal neurons to excitatory amino acids protects from later excitotoxicity.
Glutamatergic reinnervation and assembly of glutamatergic synapses in adult rat skeletal muscle occurs at cholinergic endplates.
Cannabidiol, a nonpsychotropic component of cannabis, inhibits cue-induced heroin seeking and normalizes discrete mesolimbic neuronal disturbances.
Assembly of a beta2-adrenergic receptor--GluR1 signalling complex for localized cAMP signalling.
Glucocorticoid attenuates brain-derived neurotrophic factor-dependent upregulation of glutamate receptors via the suppression of microRNA-132 expression.
Inhibition of calcineurin-mediated endocytosis and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors prevents amyloid beta oligomer-induced synaptic disruption.
Regulation of AMPA receptor trafficking by O-glycosylation.
Leptin regulates AMPA receptor trafficking via PTEN inhibition.
Binding of amyloid beta peptide to beta2 adrenergic receptor induces PKA-dependent AMPA receptor hyperactivity.
Syntaxin-4 defines a domain for activity-dependent exocytosis in dendritic spines.
Involvement of microglial P2X7 receptors and downstream signaling pathways in long-term potentiation of spinal nociceptive responses.
Regulation of nucleus accumbens activity by the hypothalamic neuropeptide melanin-concentrating hormone.
Electrical stimulation of the lateral habenula produces enduring inhibitory effect on cocaine seeking behavior.
Functional comparison of the effects of TARPs and cornichons on AMPA receptor trafficking and gating.
Role for mammalian target of rapamycin complex 1 signaling in neuroadaptations underlying alcohol-related disorders.
Hippocampal AMPA receptor gating controlled by both TARP and cornichon proteins.
Effects of food restriction and sucrose intake on synaptic delivery of AMPA receptors in nucleus accumbens.
Reinforcement-related regulation of AMPA glutamate receptor subunits in the ventral tegmental area enhances motivation for cocaine.
Crystal structure of the glutamate receptor GluA1 N-terminal domain.
Hippocampal GluA1-containing AMPA receptors mediate context-dependent sensitization to morphine.
Palmitoylation of A-kinase anchoring protein 79/150 regulates dendritic endosomal targeting and synaptic plasticity mechanisms.
PICK1 mediates transient synaptic expression of GluA2-lacking AMPA receptors during glycine-induced AMPA receptor trafficking.
Diagnostic exome sequencing in persons with severe intellectual disability.
Central amygdala GluA1 facilitates associative learning of opioid reward.
LTP requires a unique postsynaptic SNARE fusion machinery.
Acute BDNF treatment upregulates GluR1-SAP97 and GluR2-GRIP1 interactions: implications for sustained AMPA receptor expression.
A eukaryotic specific transmembrane segment is required for tetramerization in AMPA receptors.
Soluble ICAM-5, a product of activity dependent proteolysis, increases mEPSC frequency and dendritic expression of GluA1.
Region-specific alterations in glutamate receptor 1 phosphorylation during context-induced drug seeking after withdrawal from morphine self-administration.
BDNF contributes to both rapid and homeostatic alterations in AMPA receptor surface expression in nucleus accumbens medium spiny neurons.
Impact of combined prenatal ethanol and prenatal stress exposures on markers of activity-dependent synaptic plasticity in rat dentate gyrus.
Oxytocin reduces cocaine seeking and reverses chronic cocaine-induced changes in glutamate receptor function.
Persistent pain maintains morphine-seeking behavior after morphine withdrawal through reduced MeCP2 repression of GluA1 in rat central amygdala.
Activity-induced synaptic delivery of the GluN2A-containing NMDA receptor is dependent on endoplasmic reticulum chaperone Bip and involved in fear memory.
Synaptic adhesion molecule IgSF11 regulates synaptic transmission and plasticity.
Novel Roles for the Insulin-Regulated Glucose Transporter-4 in Hippocampally Dependent Memory.
Hotspots of missense mutation identify neurodevelopmental disorder genes and functional domains.
Prevention of long-term memory loss after retrieval by an endogenous CaMKII inhibitor.
Interleukin-10 and PD150606 modulate expression of AMPA receptor GluA1 and GluA2 subunits under hypoxic conditions.
Mechanisms of CPT1C-Dependent AMPAR Trafficking Enhancement.
Architecture of the heteromeric GluA1/2 AMPA receptor in complex with the auxiliary subunit TARP γ8.
Synaptic localization of C9orf72 regulates post-synaptic glutamate receptor 1 levels.
Enhanced psychostimulant response, but not social avoidance, depends on GluA1 AMPA receptors in VTA dopamine neurons following intermittent social defeat stress in rats.
Corydaline and l-tetrahydropalmatine attenuate morphine-induced conditioned place preference and the changes in dopamine D(2) and GluA1 AMPA receptor expression in rats.
Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains.
GRIP1 regulates synaptic plasticity and learning and memory.
Deep brain stimulation of the nucleus accumbens shell attenuates cocaine withdrawal but increases cocaine self-administration, cocaine-induced locomotor activity, and GluR1/GluA1 in the central nucleus of the amygdala in male cocaine-dependent rats.
Identification and functional evaluation of GRIA1 missense and truncation variants in individuals with ID: An emerging neurodevelopmental syndrome.
AMPA receptor flip/flop mutants affecting deactivation, desensitization, and modulation by cyclothiazide, aniracetam, and thiocyanate.
SEC31:SEC13 and v-SNARE recruitment
Activation of Ca impermeable AMPA receptors
Activation of Ca permeable AMPA receptors
Trafficking of GluR1-containing AMPA receptors
Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites
Trafficking of GluR2-containing AMPA receptors to synapse
Ca impermeable AMPA receptor ligand binding
Ca permeable AMPA receptor ligand binding
Activation of Ca permeable AMPA receptors
Endocytosis of Ca impermeable AMPA receptors
Membrane depolarization upon activation of Ca impermeable AMPA receptors
Nucleotide exchange on RAB1
SEC16 complex binds SAR1B:GTP:SEC23:SEC24
RAB1:GTP binds USO1 and GORASP1:GOLGA2
COPII coat binds TRAPPCII and RAB1:GDP
CSNK1D phosphorylates SEC23
BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle
Inner coat assembly and cargo binding
SALM2 associate with AMPA and NMDA receptors
UniProtKB record for GRIA1 (P42261)
GRIA1 source contexts, product identities and inference provenance
GRIA1 source guide and assay boundaries
GRIA1 independent PAINT phylogeny evidence
AMPA receptor subunit expression in the endoplasmic reticulum in frontal cortex of elderly patients with schizophrenia.