Gene Ontology annotation through association of InterPro records with GO terms
Gene Ontology annotation based on Enzyme Commission mapping
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Combined Automated Annotation using Multiple IEA Methods
Conserved tyrosine kinase promotes the import of silencing RNA into Caenorhabditis elegans cells.
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SID-3 kinase activity is required in recipient cells for efficient dsRNA import; cell-autonomous RNAi is intact.
"Thus, the kinase activity of SID-3 is essential to enable efficient import of dsRNA into C. elegans cells."
An Alternative STAT Signaling Pathway Acts in Viral Immunity in Caenorhabditis elegans.
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sid-3 mutants derepress STA-1-bound antiviral genes, placing SID-3 upstream of STA-1.
"Moreover, genes upregulated in sid-3 mutants, including those shared with sta-1, were enriched for STA-1 binding by ChIP-seq, suggesting that sid-3 acts upstream of sta-1 in the antiviral gene expression response"
An Evolutionarily Conserved Pathway Essential for Orsay Virus Infection of Caenorhabditis elegans.
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SID-3 kinase activity is required for an early pre-replication step of Orsay virus infection.
"Our experiments suggest that the kinase activity of SID-3 is important for its ability to promote Orsay virus infection."
UniProt entry Q10925 (sid-3, C. elegans)
WormBase gene description for sid-3 (worm)