Gene Ontology annotation through association of InterPro records with GO terms
Gene Ontology annotation based on Enzyme Commission mapping
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Electronic Gene Ontology annotations created by ARBA machine learning models
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Combined Automated Annotation using Multiple IEA Methods
The Borgs, a new family of Cdc42 and TC10 GTPase-interacting proteins.
Functional analysis of ARHGAP6, a novel GTPase-activating protein for RhoA.
The mammalian homologue of the Caenorhabditis elegans polarity protein PAR-6 is a binding partner for the Rho GTPases Cdc42 and Rac1.
A new family of Cdc42 effector proteins, CEPs, function in fibroblast and epithelial cell shape changes.
Plexin-B1 directly interacts with PDZ-RhoGEF/LARG to regulate RhoA and growth cone morphology.
Multifunctional roles for the PH domain of Dbs in regulating Rho GTPase activation.
TCGAP, a multidomain Rho GTPase-activating protein involved in insulin-stimulated glucose transport.
Vav GEFs are required for beta2 integrin-dependent functions of neutrophils.
A direct interaction between Cdc42 and vesicle-associated membrane protein 2 regulates SNARE-dependent insulin exocytosis.
Zizimin2: a novel, DOCK180-related Cdc42 guanine nucleotide exchange factor expressed predominantly in lymphocytes.
Local phosphatidylinositol 3,4,5-trisphosphate accumulation recruits Vav2 and Vav3 to activate Rac1/Cdc42 and initiate neurite outgrowth in nerve growth factor-stimulated PC12 cells.
E-cadherin is essential for in vivo epidermal barrier function by regulating tight junctions.
Nuclear movement regulated by Cdc42, MRCK, myosin, and actin flow establishes MTOC polarization in migrating cells.
The Rho-specific GEF Lfc interacts with neurabin and spinophilin to regulate dendritic spine morphology.
Expression, synaptic localization, and developmental regulation of Ack1/Pyk1, a cytoplasmic tyrosine kinase highly expressed in the developing and adult brain.
Membrane localization of adenomatous polyposis coli protein at cellular protrusions: targeting sequences and regulation by beta-catenin.
The Rho-GTPase cdc42 regulates neural progenitor fate at the apical surface.
Ccpg1, a novel scaffold protein that regulates the activity of the Rho guanine nucleotide exchange factor Dbs.
Proteolipid protein is required for transport of sirtuin 2 into CNS myelin.
Affixin activates Rac1 via betaPIX in C2C12 myoblast.
Bves directly interacts with GEFT, and controls cell shape and movement through regulation of Rac1/Cdc42 activity.
IQGAP3 regulates cell proliferation through the Ras/ERK signalling cascade.
FGD2, a CDC42-specific exchange factor expressed by antigen-presenting cells, localizes to early endosomes and active membrane ruffles.
ACF7 regulates cytoskeletal-focal adhesion dynamics and migration and has ATPase activity.
The phagosomal proteome in interferon-gamma-activated macrophages.
Cdo promotes neuronal differentiation via activation of the p38 mitogen-activated protein kinase pathway.
Uncovering early response of gene regulatory networks in ESCs by systematic induction of transcription factors.
The adenomatous polyposis coli-associated exchange factors Asef and Asef2 are required for adenoma formation in Apc(Min/+)mice.
ARHGEF7 (Beta-PIX) acts as guanine nucleotide exchange factor for leucine-rich repeat kinase 2.
Tinman/Nkx2-5 acts via miR-1 and upstream of Cdc42 to regulate heart function across species.
Cool-1/βPIX functions as a guanine nucleotide exchange factor in the cycling of Cdc42 to regulate insulin secretion.
DOCK8 is a Cdc42 activator critical for interstitial dendritic cell migration during immune responses.
Age-related guanine nucleotide exchange factor, mouse Zizimin2, induces filopodia in bone marrow-derived dendritic cells.
CDC42 is required for structural patterning of the lung during development.
CBAP functions as a novel component in chemokine-induced ZAP70-mediated T-cell adhesion and migration.
RAS and RHO families of GTPases directly regulate distinct phosphoinositide 3-kinase isoforms.
The lymphoid lineage-specific actin-uncapping protein Rltpr is essential for costimulation via CD28 and the development of regulatory T cells.
CDC42 switches IRSp53 from inhibition of actin growth to elongation by clustering of VASP.
CLN3 deficient cells display defects in the ARF1-Cdc42 pathway and actin-dependent events.
Essential role of sympathetic endothelin A receptors for adverse cardiac remodeling.
Phosphoinositide 3-kinase p85beta regulates invadopodium formation.
The RhoGEF DOCK10 is essential for dendritic spine morphogenesis.
Association of dysfunctional synapse defective 1 (SYDE1) with restricted fetal growth - SYDE1 regulates placental cell migration and invasion.
Cdc42 activation by endothelin regulates neural crest cell migration in the cardiac outflow tract.
Photoactivatable CaMKII induces synaptic plasticity in single synapses.
Biallelic variants in IQCN cause sperm flagellar assembly defects and male infertility.
Oncogene ect2 is related to regulators of small GTP-binding proteins.
Activation of CDC42 by intersectin-1
Activation of WASP and N-WASP by CDC42
Interaction of Bnip-2 with Cdc42
Falcon deep research summary for mouse Cdc42