GCV2 notes (YMR189W, P49095)
- P-protein, glycine dehydrogenase (decarboxylating), EC 1.4.4.2, PLP enzyme [UniProt:P49095]; cloned via gsd2 PMID:8830251.
- Glycine-induced; GDC activity rises in glycine PMID:8830251.
- Early biochemistry: PMID:320197 (abstract does not name the gene; SGD IDA attached to GCV2; deferred to curator).
Curation observations
- RCA cytosol -> REMOVE (mitochondrial complex).
2026-11-10 glycine cleavage module completion pass (Claude, AI-assisted)
- Every row now carries a verbatim supporting quote; truncated UniProt quotes were completed to the end of the claim.
- Broad parent rows shared across the module's P/H/T/L reviews were harmonized: glycine metabolic/catabolic process (and amino acid metabolic process) -> MODIFY to GO:0019464; for the L proteins 2-oxoglutarate metabolic process and tricarboxylic acid cycle -> MODIFY to GO:0120551, generic oxidoreductase parents -> MODIFY to GO:0004148, FAD binding ACCEPT.