Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
BcsQ is an essential component of the Escherichia coli cellulose biosynthesis apparatus that localizes at the bacterial cell pole.
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The study identifies BcsQ as a polar cellulose-biosynthesis accessory.
"we demonstrate that BcsQ, a MinD homologue, displays a polar localization"
Cellulose as an architectural element in spatially structured Escherichia coli biofilms.
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The codon 6 stop was repaired in W3110 to create cellulose-producing AR3110.
"For changing codon 6 of bcsQ from TAG(stop) to TTG(leucine) in the chromosomal copy of bcsQ in strain W3110"
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BcsA deletion tests cellulose synthesis in the repaired background.
"a precise deletion of the cellulose synthase gene bcsA in AR3110 reconstituted the ring-structured morphology previously observed for strain W3110"
Structural basis for synthase activation and cellulose modification in the E. coli Type II Bcs secretion system.
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E. coli structures distinguish catalytic BcsA, membrane-anchored BcsB and cytosolic BcsQ stabilization.
"BcsQ buttresses the PilZ domain, likely stabilizing the catalytically competent state."
Architecture and regulation of an enterobacterial cellulose secretion system.
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BcsRQ forms nucleotide-loaded dimers in structures.
"BcsRQ crystallized as ATP-bound “sandwich” or “tango” dimers of heterodimers."
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Wild-type hydrolysis is weak and regulated; downstream coupling remains a model.
"the BcsHisRQWT complex exhibited only weak adenosine triphosphatase (ATPase) activity in vitro"
UniProt P37655 reference-proteome pseudogene-fragment record
BcsQ record comparison and allele provenance