Characterization of five novel Pseudomonas aeruginosa cell-surface signalling systems.
-
PA4896 was overexpressed and its target genes identified by microarray, proteomics and/or lacZ reporters.
"the ECF sigmas PA0149, PA1912, PA2050, PA2093 and PA4896 have been overexpressed and their target gene candidates have been identified using DNA microarray, proteomic analysis, and/or lacZ reporter construct"
-
Each of the five sigma factors drives production of one TonB-dependent transducer; the target transport systems are only putatively metal-related.
"although all these sigma factors seem to control putative (metal) transport systems"
A Novel extracytoplasmic function (ECF) sigma factor regulates virulence in Pseudomonas aeruginosa.
-
General description of sigma factor function in P. aeruginosa CSS systems.
"Sigma factors are essential subunits of prokaryotic RNA polymerase, they are involved in promoter recognition and transcription initiation"
Extracytoplasmic function sigma factors in Pseudomonas aeruginosa.
-
Review grouping the P. aeruginosa ECF sigma factors by function.
"the iron starvation σ (PvdS, FpvI, HasI, FecI, FecI2 and others), the cell wall stress ECFσ AlgU, SigX and SbrI, and the unorthodox σVreI involved in the expression of virulence"
Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Automatic assignment of GO terms using logical inference, based on on inter-ontology links
UniProt entry for PA4896 (PA4896)